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感染性心内膜炎伴脾栓塞性梗死、肾梗死和椎间盘炎

Infective Endocarditis Presenting with Embolic Splenic and Renal Infarcts and Spinal Discitis.

作者信息

Vasconcellos David, Weng Bruce, Wu Patrick, Thompson Gary, Sutjita Made

机构信息

University of California, Riverside School of Medicine, Los Angeles, California, USA.

Department of Internal Medicine, Riverside University Health System Medical Center, Moreno Valley, California, USA.

出版信息

Case Rep Infect Dis. 2022 May 14;2022:7183049. doi: 10.1155/2022/7183049. eCollection 2022.

DOI:10.1155/2022/7183049
PMID:35607353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9124120/
Abstract

(. ) is a Gram-positive, coagulase-negative bacteria that occurs as a normal commensal organism on the skin and may rarely cause native valve endocarditis (NVE). We present a 62-year-old male with type 2 diabetes mellitus, coronary artery disease, and hypertension presenting with fever and abdominal pain. CT (computerized tomography) of the abdomen revealed splenic and renal infarcts; further imaging with MRI (magnetic resonance imaging) revealed enhancements consistent with discitis in T5-6 and L1-2. Three sets of blood cultures were positive for . sensitive to methicillin on antimicrobial susceptibility tests, and echocardiogram showed posterior mitral valve vegetation. The patient was initially treated with 10 weeks of nafcillin IV (intravenous) 2 g q4 hours. He had recurrent bouts of S. bacteremia that was treated with IV vancomycin. His clinical course was complicated by new-onset atrial fibrillation with rapid ventricular response and congestive heart failure. Once bacteremia was cleared, his infective endocarditis was successfully definitively treated with mitral valve replacement and tricuspid repair.

摘要

(.)是一种革兰氏阳性、凝固酶阴性细菌,作为皮肤正常共生菌存在,很少引起自体瓣膜心内膜炎(NVE)。我们报告一名62岁男性,患有2型糖尿病、冠状动脉疾病和高血压,出现发热和腹痛。腹部CT(计算机断层扫描)显示脾梗死和肾梗死;进一步的MRI(磁共振成像)检查显示T5 - 6和L1 - 2椎体炎相关的强化表现。三组血培养结果显示(.)阳性。药敏试验显示其对甲氧西林敏感,超声心动图显示二尖瓣后叶赘生物。患者最初接受了为期10周的静脉注射萘夫西林治疗,剂量为每4小时2克。他反复出现(.)菌血症,接受静脉注射万古霉素治疗。他的临床病程因新发快速心室率心房颤动和充血性心力衰竭而复杂化。一旦菌血症清除,他的感染性心内膜炎通过二尖瓣置换和三尖瓣修复成功得到根治。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/d7d3a7b7bbac/CRIID2022-7183049.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/2c3fb6eb1cbf/CRIID2022-7183049.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/f00e0b29f199/CRIID2022-7183049.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/7684be296522/CRIID2022-7183049.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/58fbb7b5160b/CRIID2022-7183049.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/d7d3a7b7bbac/CRIID2022-7183049.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/2c3fb6eb1cbf/CRIID2022-7183049.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/f00e0b29f199/CRIID2022-7183049.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/7684be296522/CRIID2022-7183049.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/58fbb7b5160b/CRIID2022-7183049.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/9124120/d7d3a7b7bbac/CRIID2022-7183049.005.jpg

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