Gaiduchevici Alina Elena, Cîrstoveanu Cătălin Gabriel, Socea Bogdan, Bizubac Ana Michaela, Herișeanu Carmen Mariana, Filip Cristina, Mihălțan Florin Dumitru, Dimitriu Mihai, Jacotă-Alexe Florentina, Ceaușu Mihail, Spătaru Radu-Iulian
Neonatal Intensive Care Unit, 'Maria S. Curie' Emergency Clinic Hospital for Children, 077120 Bucharest, Romania.
Discipline of Pediatrics, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Exp Ther Med. 2022 Jun;23(6):436. doi: 10.3892/etm.2022.11363. Epub 2022 May 10.
The present study presents the experience gained in the Newborn Intensive Care Unit (NICU) of 'Maria S. Curie' Emergency Clinical Hospital for Children in Bucharest (Romania) after performing a series of bedside surgery interventions on newborns with congenital diaphragmatic hernia (CDH). We conducted a retrospective analysis of the data for all patients operated on-site between 2011 and 2020, in terms of pre- and post-operative stability, procedures performed, complications and outcomes. An analysis of a control group was used to provide a reference to the survival rate for non-operated patients. The present study is based on data from 10 cases of newborns, surgically operated on, on average, on the fifth day of life. The main reasons for operating on-site included hemodynamical instability and the need to administer inhaled nitric oxide (iNO) and high-frequency oscillatory ventilation (HFOV). There were no unforeseen events during surgery, no immediate postoperative complications and no surgery-related mortality. One noticed drawback was the unfamiliarity of the surgery team with the new operating environment. Our experience indicates that bedside surgery improves the likelihood of survival for critically ill neonates suffering from CDH. No immediate complications were associated with this practice.
本研究介绍了罗马尼亚布加勒斯特“玛丽亚·S·居里”儿童急诊临床医院新生儿重症监护病房（NICU）在对先天性膈疝（CDH）新生儿进行一系列床边手术干预后所获得的经验。我们对2011年至2020年间所有在现场接受手术的患者的数据进行了回顾性分析，内容包括术前和术后的稳定性、所实施的手术程序、并发症及结果。通过对一个对照组的分析，为未接受手术患者的存活率提供参考。本研究基于10例接受手术的新生儿数据，这些新生儿平均在出生后第五天接受手术。现场手术的主要原因包括血流动力学不稳定以及需要使用吸入一氧化氮（iNO）和高频振荡通气（HFOV）。手术期间未发生意外事件，术后无即刻并发症，也无手术相关死亡病例。一个明显的缺点是手术团队对新的手术环境不熟悉。我们的经验表明，床边手术提高了患有CDH的危重新生儿的存活可能性。这种做法未引发即刻并发症。
