Kuck H, Stärk N
Klin Monbl Augenheilkd. 1986 Dec;189(6):460-2. doi: 10.1055/s-2008-1050853.
Of 246 systematically screened prematurely born infants, the majority with high neonatological risk, 12 developed a retinopathy of prematurity of at least Stage 3 according to the international classification of 1984, and underwent transconjunctival cryocoagulation. At a follow-up examination at age 6 months and later, there were no retinal changes apart from coagulation scars in 7 of the treated eyes; in 7 eyes slight connective tissue proliferations were seen (stage 1 cicatrization), in 4 eyes peripheral connective tissue proliferations with macula traction (stage 2 cicatrization), and stage 4 or 5 cicatrization in 2 eyes each. Five eyes were myopic, 2 of them severely so, and 4 eyes had a positive gamma angle. Unfavorable prognosis was indicated by a large avascular zone, preoperative stage 4, and early occurrence and rapid progression of retinopathic stages.
在246名经过系统筛查的早产儿中,大多数具有较高的新生儿科风险,根据1984年国际分类标准,有12名早产儿发生了至少3期的早产儿视网膜病变,并接受了经结膜冷凝治疗。在6个月及以后的随访检查中,7只接受治疗的眼睛除了有凝固瘢痕外没有视网膜变化;7只眼睛出现了轻微的结缔组织增生(1期瘢痕形成),4只眼睛出现了伴有黄斑牵拉的周边结缔组织增生(2期瘢痕形成),2只眼睛分别出现了4期或5期瘢痕形成。5只眼睛近视,其中2只高度近视,4只眼睛的γ角为阳性。无血管区大、术前4期以及视网膜病变阶段早期出现和快速进展提示预后不良。