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穹窿型和鞍背型ST段抬高:Brugada综合征拟表型与Brugada综合征

Coved and Saddleback ST-Segment Elevations: Brugada Phenocopy vs Brugada Syndrome.

作者信息

McCullough Jocelyn, McCullough Joseph, Gonzalez Marcella

机构信息

Medical Education, Zucker School of Medicine, Hempstead, USA.

Hospital Medicine, Zucker School of Medicine, Hempstead, USA.

出版信息

Cureus. 2022 Apr 21;14(4):e24338. doi: 10.7759/cureus.24338. eCollection 2022 Apr.

Abstract

We report a case of a middle-aged man who presented with near syncope, fever, and dysuria and was incidentally found to have coved ST-segment elevations in leads V1 and V2 confirming Brugada type 1 ECG (electrocardiogram) pattern. This ECG pattern morphed into saddleback ST-segment elevations in precordial leads consistent with type 2 Brugada the following day. Additionally, the patient reported a positive family history of sudden cardiac death. This initial presentation made it impossible to differentiate Brugada phenocopy (BrP) from Brugada syndrome (BrS). Continuous cardiac monitoring was initiated, electrophysiology consulted and fever managed with antipyretics. The patient was diagnosed with prostatitis and bacteremia from E. coli and managed with antibiotics. There were no electrolyte abnormalities nor was the patient on any medications other than tamsulosin for his chronic benign prostate hypertrophy. Once the fever resolved the patient's ECG returned to normal, thus confirming the diagnosis of BrS on day 3 post-admission. Differentiating between BrP and BrS requires ruling out possible underlying causes and determining if resolution in ECG patterns occurs.

摘要

我们报告了一例中年男性病例,该患者出现近似晕厥、发热和排尿困难,偶然发现V1和V2导联出现穹窿样ST段抬高,确诊为1型Brugada心电图(ECG)模式。次日,这种ECG模式演变为胸前导联的鞍背样ST段抬高,符合2型Brugada。此外,患者报告有心脏性猝死的家族史阳性。这一初始表现使得无法区分Brugada拟表型(BrP)和Brugada综合征(BrS)。开始进行持续心脏监测,咨询电生理科并使用退烧药控制发热。患者被诊断为大肠杆菌引起的前列腺炎和菌血症,并使用抗生素治疗。除了用于治疗慢性良性前列腺增生的坦索罗辛外,患者没有电解质异常,也未服用其他任何药物。发热消退后,患者的ECG恢复正常,从而在入院后第3天确诊为BrS。区分BrP和BrS需要排除可能的潜在病因,并确定ECG模式是否恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/9123839/4aa7b60a267b/cureus-0014-00000024338-i01.jpg

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