与院外心脏骤停相关的Brugada综合征：一例报告。
Brugada syndrome associated with out-of-hospital cardiac arrest: A case report.
作者信息
Ni Guo-Hua, Jiang Hua, Men Li, Wei Yuan-Yuan, A Dila, Ma Xiang
机构信息
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Chengdu Jinjiang Sohome Comprehensive Outpatient Clinic), Chengdu 610072, Sichuan Province, China.
Department of Geriatrics, Affiliated Hospital of Chengdu University, Chengdu 610081, Sichuan Province, China.
出版信息
World J Clin Cases. 2021 Jul 6;9(19):5345-5351. doi: 10.12998/wjcc.v9.i19.5345.
BACKGROUND
Brugada syndrome (BrS) is an inherited disease characterized by an electrocardiogram (ECG) with a coved-type ST-segment elevation in the right precordial leads (V1-V3), which predisposes to sudden cardiac death (SCD) due to polymorphic ventricular tachycardia or ventricular fibrillation in the absence of structural heart disease. We report the case of a 29-year-old man with out-of-hospital cardiac arrest. BrS is associated with a high incidence of SCD in adults, and increasing the awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.
CASE SUMMARY
A 29-year-old man suffered from out-of-hospital cardiac arrest, and after defibrillation, his ECG demonstrated a coved-type elevated ST segment in V1 and V2. These findings were compatible with type 1 Brugada pattern, and ECG of his brother showed a type 2 Brugada pattern. The diagnosis was BrS, NYHF IV, multiple organ dysfunction syndrome, sepsis, and hypoxic ischemic encephalopathy. The patient had no arrhythmia episodes after discharge throughout a follow-up period of 36 mo.
CONCLUSION
Increasing awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.
背景
Brugada综合征（BrS）是一种遗传性疾病，其特征为心电图（ECG）显示右胸前导联（V1-V3）出现穹窿型ST段抬高，在无结构性心脏病的情况下，易因多形性室性心动过速或心室颤动而导致心源性猝死（SCD）。我们报告一例29岁院外心脏骤停男性病例。BrS在成年人中与SCD的高发病率相关，提高对BrS的认识并及时识别Brugada心电图模式可挽救生命。
病例摘要
一名29岁男性发生院外心脏骤停，除颤后其心电图显示V1和V2导联ST段穹窿型抬高。这些表现符合1型Brugada模式，其兄弟的心电图显示2型Brugada模式。诊断为BrS、纽约心脏协会（NYHA）心功能IV级、多器官功能障碍综合征、脓毒症和缺氧缺血性脑病。在36个月的随访期内，患者出院后未发生心律失常事件。
结论
提高对BrS的认识并及时识别Brugada心电图模式可挽救生命。
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