From the Department of Biostatistics and Epidemiology, University of North Texas Health Science Center, Fort Worth, TX.
Department of Social and Behavioral Sciences, College of Public Health, Temple University, Philadelphia, PA.
Sex Transm Dis. 2022 Jun 1;49(6):423-428. doi: 10.1097/OLQ.0000000000001615. Epub 2022 Feb 8.
Previous human papillomavirus (HPV) and HPV vaccine knowledge scales have focused on young adults in the vaccination catch-up age range or parents of vaccine eligible adolescents. Previous scales are not specific to the new guidelines for HPV vaccination in mid-adults. The study aimed to develop and validate a mid-adult HPV vaccine knowledge scale informed by the latest vaccine recommendations.
Self-reported data were collected using a cross-sectional survey of adults aged 27 to 45 years with no history of HPV vaccination (n = 706). Exploratory and confirmatory factor analyses identified latent constructs in a 13-item mid-adult HPV vaccine knowledge scale. Sociodemographic differences in the HPV vaccine knowledge were also assessed.
The mean of correct responses across all items was 5.9 (SD, 2.8; range, 0-13). Exploratory and confirmatory factor analyses revealed a 3-factor structure best explained the data with a good construct validity and reliability. The first factor contained 6 items about HPV infection, the second factor contained 3 items about HPV prevention through vaccination, and the third factor contained items about HPV vaccination misinformation. Analysis of variance and t test found significant group level differences in knowledge among sex, race, educational level, annual income, health insurance, and marital status.
Our study supports the use of a knowledge scale for US mid-adults to assess HPV and HPV vaccination knowledge because the patient requires some baseline knowledge of this recommendation to discuss the vaccine with their health care provider. The mid-adult HPV vaccine knowledge scale can measure basic HPV knowledge important to informed decision making.
以往的人乳头瘤病毒（HPV）和 HPV 疫苗知识量表主要集中在接种补种年龄范围内的年轻人或疫苗合格青少年的父母身上。以往的量表与新的中年人 HPV 疫苗接种指南并不具体。本研究旨在开发和验证一种基于最新疫苗推荐的中年人 HPV 疫苗知识量表。
使用一项针对 27 至 45 岁、无 HPV 疫苗接种史的成年人（n=706）的横断面调查，收集自我报告数据。探索性和验证性因子分析确定了 13 项中年人 HPV 疫苗知识量表中的潜在结构。还评估了 HPV 疫苗知识在社会人口统计学方面的差异。
所有项目的正确反应平均值为 5.9（SD，2.8；范围，0-13）。探索性和验证性因子分析显示，三因素结构最能解释数据，具有良好的结构效度和信度。第一个因素包含 6 个关于 HPV 感染的项目，第二个因素包含 3 个关于通过疫苗预防 HPV 的项目，第三个因素包含关于 HPV 疫苗错误信息的项目。方差分析和 t 检验发现，在性别、种族、教育程度、年收入、医疗保险和婚姻状况方面，知识方面存在显著的群体差异。
我们的研究支持使用美国中年人 HPV 疫苗知识量表来评估 HPV 和 HPV 疫苗知识，因为患者需要对这一建议有一些基本的了解，以便与他们的医疗保健提供者讨论疫苗。中年人 HPV 疫苗知识量表可以衡量对知情决策很重要的基本 HPV 知识。
