Solberg L A, Ishii T, Strong J P, Guzman M A, Hosoda Y, Tsugane S, Newman W P, Tracy R E
Lab Invest. 1987 Apr;56(4):451-6.
We compared the extent of lesions in the coronary arteries of autopsied middle-aged men from Oslo, Norway, with lesions in autopsied men of similar ages in Tokyo, Japan. Certain risk factors for coronary heart disease as serum cholesterol, triglycerides, and blood pressure were also available from these men in the two locations. Our comparisons reveal large differences in the extent of atherosclerosis between Oslo and Tokyo, which are reflected in the levels of the risk factors, particularly serum cholesterol levels. Our findings suggest that preventive strategies could retard the development of atherosclerosis and coronary heart disease without the economic and nutritional problems that affect technically underdeveloped societies where atherosclerosis and coronary heart disease are not prevalent.
我们比较了挪威奥斯陆尸检的中年男性冠状动脉中的病变程度，以及日本东京年龄相仿的尸检男性的病变程度。这两地的这些男性还提供了某些冠心病风险因素，如血清胆固醇、甘油三酯和血压。我们的比较揭示了奥斯陆和东京在动脉粥样硬化程度上的巨大差异，这在风险因素水平上有所体现，尤其是血清胆固醇水平。我们的研究结果表明，预防策略可以延缓动脉粥样硬化和冠心病的发展，而不会带来影响技术欠发达社会的经济和营养问题，在这些社会中动脉粥样硬化和冠心病并不普遍。
