Martinez A P, Mobley W P, Witte C L
Lymphology. 1986 Dec;19(4):168-9.
Constriction of the thoracic inferior vena cava is a useful experimental maneuver to reproduce massive ascites. Unfortunately, the margin of safety of this technique is narrow in that too much constriction overly restricts venous return with subsequent shock and death, and lesser constriction is often associated with extensive venous collateralization via the azygos system and failure to sustain hepatic congestion. By combining azygos vein ligation with 50% constriction of the supradiaphragmatic inferior vena caval circumference at the time of the initial thoracotomy, we have found that intense hepatic congestion is sustained and that dogs consistently develop massive ascites within 2-3 weeks.
缩窄胸段下腔静脉是一种用于重现大量腹水的有用实验手段。不幸的是，该技术的安全范围很窄，因为过度缩窄会过度限制静脉回流，继而导致休克和死亡，而缩窄程度较小则常伴有通过奇静脉系统形成广泛的静脉侧支循环，且无法维持肝淤血。通过在初次开胸时将奇静脉结扎与膈上5腔静脉周径50%的缩窄相结合，我们发现肝淤血得以持续，并且犬在2至3周内持续出现大量腹水。
