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[从尿路感染分离出的革兰氏阴性菌对酰脲类青霉素的体外敏感性]

[In vitro susceptibility of gram-negative bacteria isolated from urinary tract infections to acylureidopenicillins].

作者信息

Cerikcioğlu N, Ustaçelebi S, Günalp A

出版信息

Mikrobiyol Bul. 1986 Jul;20(3):139-44.

PMID:3561279
Abstract

Ureidopenicillins exert antibacterial activity on many Gram negative bacteria and also some Gram positive bacteria Two acylureido penicillins called azlocillin and mezlocillin have been introduced recently into medical practice in many countries as broad spectrum antibiotics. In this communication we present the sensitivity of Gram negative bacteria isolated from urinary tract infection of pediatric age patients to azlocillin, mezlocillin, another semisynthetic penicillin called pipercillin and aminoglycoside antibiotic gentamicin by MIC and disk-diffusion methods. The results are discussed in the view of the use of new semisythetic penicillins in clinical practice.

摘要

脲基青霉素对许多革兰氏阴性菌以及一些革兰氏阳性菌具有抗菌活性。两种酰脲基青霉素,即阿洛西林和美洛西林,最近在许多国家作为广谱抗生素被引入医学实践。在本交流中,我们通过微量肉汤稀释法(MIC)和纸片扩散法,展示了从儿科患者尿路感染中分离出的革兰氏阴性菌对阿洛西林、美洛西林、另一种半合成青霉素哌拉西林以及氨基糖苷类抗生素庆大霉素的敏感性。从临床实践中使用新型半合成青霉素的角度对结果进行了讨论。

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