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沃尔巴克氏体蛋白引起细胞质不亲和性的复杂动力学。

Perplexing dynamics of Wolbachia proteins for cytoplasmic incompatibility.

机构信息

Hakubi Center for Advanced Research, Kyoto University, Kyoto, Japan.

Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

出版信息

PLoS Biol. 2022 May 25;20(5):e3001644. doi: 10.1371/journal.pbio.3001644. eCollection 2022 May.

DOI:10.1371/journal.pbio.3001644
PMID:35613073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9132339/
Abstract

The mechanism of symbiont-induced cytoplasmic incompatibility (CI) has been a long-standing mystery. A new study on Wolbachia's Cif proteins in PLOS Biology provides supportive evidence for the "Host modification model," although the alternative "Toxin-antidote model" is still in the running.

摘要

共生体诱导细胞质不亲和性(CI)的机制一直是一个长期存在的谜团。PLOS Biology 上一项关于沃尔巴克氏体 Cif 蛋白的新研究为“宿主修饰模型”提供了支持性证据,尽管替代的“毒素-解毒剂模型”仍在竞争中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/9132339/a6262afd704e/pbio.3001644.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/9132339/a6262afd704e/pbio.3001644.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/9132339/a6262afd704e/pbio.3001644.g001.jpg

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PLoS Biol. 2022 May 24;20(5):e3001584. doi: 10.1371/journal.pbio.3001584. eCollection 2022 May.
2
Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue.沃尔巴克氏体 CidA 和 CidB 的晶体结构揭示了细菌诱导的细胞质不亲和性和拯救的决定因素。
Nat Commun. 2022 Mar 25;13(1):1608. doi: 10.1038/s41467-022-29273-w.
3
Paternal transmission of the Wolbachia CidB toxin underlies cytoplasmic incompatibility.
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