在英国一个县进行的 1220 例恶性眼周肿瘤的 5 年回顾。
A 5-year review of 1220 malignant periocular tumours in an English county.
机构信息
University Hospital Southampton, Southampton, UK.
James Paget University Hospital, Great Yarmouth, UK.
出版信息
Eye (Lond). 2023 Apr;37(6):1271-1274. doi: 10.1038/s41433-022-02113-3. Epub 2022 May 25.
BACKGROUND/OBJECTIVES: To determine the incidence, proportion and location of periocular tumours in an English county over a five year period, and compare to other studies in the UK and worldwide.
SUBJECTS/METHODS: A retrospective review of histopathology reports was performed for all periocular excision biopsies of malignancies from the county's three main hospitals over a 5-year period. These hospitals cover a population of just over one million. Tumours were classified according to type and location.
RESULTS
1220 lesions were included in this study. Right-sided lesions were more common than left. The incidence of basal cell carcinoma was 22 per 100,000 and squamous cell carcinoma 1.3 per 100,000, which were found most commonly on the lower eyelid and eyebrow respectively. The incidences of all other types of lesions were less than 0.5 per 100,000 per year.
CONCLUSIONS
The incidence of periocular basal cell carcinomas in the predominantly elderly Caucasian population was at least three times the published national average. The high incidence of periocular tumours in this North East Anglian county is set to increase further as the proportion of over 65 year olds in the population is predicted to nearly double within two decades.
背景/目的：确定在英国一个县的五年期间眼部周围肿瘤的发病率、比例和位置，并与英国和全球其他研究进行比较。
研究对象/方法：对该县三家主要医院五年间眼部周围恶性肿瘤切除活检的组织病理学报告进行回顾性分析。这些医院覆盖了略超过一百万人的人口。肿瘤根据类型和位置进行分类。
结果
本研究共纳入 1220 例病变。右侧病变比左侧更常见。基底细胞癌的发病率为每 10 万人 22 例，鳞状细胞癌为每 10 万人 1.3 例，分别最常见于下眼睑和眉毛。其他类型病变的发病率均低于每年每 10 万人 0.5 例。
结论
在以白种老年人为主的人群中，眼部周围基底细胞癌的发病率至少是全国平均水平的三倍。由于预计未来二十年该地区 65 岁以上人口比例将几乎翻一番，东北安格利亚郡眼部周围肿瘤的高发率预计将进一步上升。
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