Al Wohaib Manar, Al Ahmadi Reem, Al Essa Dalal, Maktabbi Azza, Khandekar Rajiv, Al Sharif Eman, Al Katan Hind, Schellini Silvana Artioli, Al Shaikh Osama
Department of Oculoplastic, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Department of Education, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Middle East Afr J Ophthalmol. 2018 Apr-Jun;25(2):96-102. doi: 10.4103/meajo.MEAJO_305_17.
Data on basal cell carcinoma (BCC) from the Middle East are deficient. We present the features and management outcomes for BCC over the last 36 years in Saudi Arabia.
This retrospective chart review included BCC patients diagnosed and treated at Saudi Arabia between 1980 and 2016. Data were collected on patient demographics, clinical and histopathological characteristics of the lesions, management, and follow-up.
One hundred and twenty-six patients with BCC were included in this study. The incidence of BCC in Saudi Arabia is 0.8 cases a year. The median age of the patients was 71 years. BCC affected 58.9% of males. The lower lid was the most common site of occurrence (52.7%). Clinically, BCC was most commonly recognized as a mixed lesion (41.1%) and 50.4% were histologically nodular. Risk factors for poor prognosis included tumor localization in the medial aspect of the lid, tumor size > 5 mm, histological subtype being ulcerative or morphea forms, affected margins, and recurrent lesions.
BCC is a rare condition in Saudi Arabia. The clinical features and histopathology of BCC in Saudi Arabia are similar to the patterns observed in other regions of the world. Early detection and timely management mitigates the extensive destructive ocular/orbital damage due to BCC and results in better patient outcomes.
中东地区基底细胞癌（BCC）的数据不足。我们展示了沙特阿拉伯过去36年中基底细胞癌的特征及治疗结果。
这项回顾性图表审查纳入了1980年至2016年在沙特阿拉伯诊断和治疗的基底细胞癌患者。收集了患者的人口统计学数据、病变的临床和组织病理学特征、治疗方法及随访情况。
本研究纳入了126例基底细胞癌患者。沙特阿拉伯基底细胞癌的发病率为每年0.8例。患者的中位年龄为71岁。基底细胞癌在男性中的发病率为58.9%。下眼睑是最常见的发病部位（52.7%）。临床上，基底细胞癌最常被诊断为混合型病变（41.1%），组织学上50.4%为结节型。预后不良的危险因素包括肿瘤位于眼睑内侧、肿瘤大小>5mm、组织学亚型为溃疡性或硬斑病样、切缘受累及复发性病变。
基底细胞癌在沙特阿拉伯较为罕见。沙特阿拉伯基底细胞癌的临床特征和组织病理学与世界其他地区观察到的模式相似。早期发现和及时治疗可减轻基底细胞癌所致的广泛破坏性眼/眶损伤，并带来更好的患者预后。
