Department of Cardiology, First Affiliated Hospital of Suzhou University, Suzhou, Jiangsu 215008, China.
Comput Math Methods Med. 2022 May 16;2022:8695291. doi: 10.1155/2022/8695291. eCollection 2022.
To explore the effect of implantable cardioverter defibrillator/cardiac resynchronization therapy defibrillator (ICD/CRT-D) implantation on adverse events and the readmission rate in patients with chronic heart failure (CHF).
Sixty patients with CHF treated in our hospital from April 2019 to July 2021 were enrolled. The patients were randomly assigned into the control group and study group. The control group received routine intervention, and the study group received remote management with ICD/CRT-D implantation.
First of all, we compared the general data of the two groups. There was no significant difference in LVEF, NYHA grade, concomitant disease, and history of arrhythmia ( > 0.05). Secondly, we compared the end-point events. In the study group, 5 cases of heart failure were readmitted, 0 cases died, and 4 cases were admitted to hospital with arrhythmia and ICD events, with a total incidence of 30.0%, while in the control group, 12 cases were rehospitalized with heart failure, 3 cases died, 25 cases were admitted with arrhythmia and ICD events, and the total incidence rate was 56.67% ( < 0.05). In terms of the readmission rate of patients with heart failure in grade NYHAII and grade III, among the patients with grade NYHAII, the number of patients with heart failure less than once in the study group was higher compared to that in the control group and the number of patients with heart failure ≥ once in the study group was lower compared to that in the control group ( < 0.05). Among the patients with grade NYHAIII, the number of patients with heart failure less than once in the study group was higher compared to that in the control group and the number of patients with heart failure ≥ once in the study group was lower compared to that in the control group. There exhibited no significant difference in the data ( > 0.05). Considering the occurrence of VT and VF events, the study team reported that 14 patients recorded a total of 276 ventricular arrhythmias: 261 ventricular tachycardia and 15 ventricular fibrillations. Among them, 24 VT (9.2%) and 4 VF (26.7%) were determined to be misrecognition of the equipment. A total of 178 ventricular arrhythmias were recorded in 13 patients in the control group, including 152 ventricular tachycardia and 26 ventricular fibrillations. Among them, 10 VT (6.6%) and 8 VF (30.8%) were determined as misrecognition of the device. In regard to the treatment results of the two groups, after admission to the hospital for radio frequency, ablation, and adjustment of drug treatment to reprogram control, the patients did not reappear to have CRT-D misidentification and misdischarged. Finally, we compared the diagnosis time of VT/VE events. The time from VT/VE events to diagnosis in 14 patients in the study group was 2.55 ± 1.41 days, and that in 13 patients in the control group was 37.32 ± 15.31 days. The discovery of ICD events in the study group was significantly earlier compared to that in the routine follow-up group ( < 0.05). This gives doctors enough time to assess the patient's condition and determine a further diagnosis and treatment plan.
Using ICD/CRT-D implantation to remotely monitor patients with CHF, through remote monitoring of the 24-hour average heart rate and the heart rate at rest and patient activity and other parameters and early intervention, the readmission rate caused by the deterioration of heart failure can be reduced. Compared with routine follow-up, remote monitoring significantly reduced the diagnosis time of VT/VE events.
探讨植入式心脏复律除颤器/心脏再同步治疗除颤器(ICD/CRT-D)植入对慢性心力衰竭(CHF)患者不良事件和再入院率的影响。
选取我院 2019 年 4 月至 2021 年 7 月收治的 60 例 CHF 患者,采用随机数字表法将患者分为对照组和研究组,对照组给予常规干预,研究组给予 ICD/CRT-D 植入远程管理。
首先,比较两组一般资料,两组 LVEF、NYHA 分级、合并疾病、心律失常史比较,差异无统计学意义(>0.05)。其次,比较终点事件,研究组心力衰竭再入院 5 例,死亡 0 例,心律失常和 ICD 事件入院 4 例,总发生率为 30.0%,对照组心力衰竭再入院 12 例,死亡 3 例,心律失常和 ICD 事件入院 25 例,总发生率为 56.67%(<0.05)。在 NYHAⅡ级和 NYHAⅢ级心力衰竭患者的再入院率方面,NYHAⅡ级患者中,研究组心力衰竭<1 次入院例数多于对照组,心力衰竭≥1 次入院例数少于对照组(<0.05);NYHAⅢ级患者中,研究组心力衰竭<1 次入院例数多于对照组,心力衰竭≥1 次入院例数少于对照组(<0.05)。考虑 VT 和 VF 事件的发生,研究组报告 14 例患者共记录 276 次室性心律失常:261 次室性心动过速和 15 次心室颤动。其中,24 次 VT(9.2%)和 4 次 VF(26.7%)被确定为设备误识别。对照组 13 例患者共记录 178 次室性心律失常,包括 152 次室性心动过速和 26 次心室颤动。其中,10 次 VT(6.6%)和 8 次 VF(30.8%)被确定为设备误识别。两组治疗结果比较,入院后行射频消融、调整药物治疗程控复律后,两组患者均未再出现 CRT-D 误识别和误放电。最后,比较 VT/VE 事件的诊断时间,研究组 14 例患者 VT/VE 事件至诊断的时间为 2.55±1.41 天,对照组 13 例患者为 37.32±15.31 天。研究组 ICD 事件的发现明显早于常规随访组(<0.05)。这为医生提供了足够的时间来评估患者的病情,并确定进一步的诊断和治疗计划。
采用 ICD/CRT-D 植入对 CHF 患者进行远程监测,通过远程监测 24 小时平均心率、静息心率、患者活动等参数和早期干预,可以降低因心力衰竭恶化而导致的再入院率。与常规随访相比,远程监测显著缩短了 VT/VE 事件的诊断时间。