Department of Medical Ultrasound, Qingpu Brance of Zhongshan Hospital, Fudan University School of Medicine, No. 1158 East Park Road, Shanghai 201700, China.
Contrast Media Mol Imaging. 2022 May 9;2022:6425145. doi: 10.1155/2022/6425145. eCollection 2022.
To compare the clinical value of contrast-enhanced ultrasound and conventional ultrasound-guided puncture biopsy in peripulmonary lesions of different sizes.
110 patients with peripulmonary lesions were randomly divided into two groups: the conventional ultrasound-guided group and the contrast-enhanced ultrasound-guided group. The lesions in the two groups were further divided into two groups according to the size of the lesions, and the tissues taken after puncture biopsy were sent for pathological examination. The pathological results were compared with the postoperative pathological results and other examination results, and the complications were recorded at the same time.
In the conventional ultrasound group, the success rate of single puncture was 72.7% and the success rate of puncture was 80.0%; in the contrast group, the success rate of single puncture was 90.9% and the success rate of puncture was 94.6%. The difference between the two groups was statistically significant. There was no significant difference in needle bleeding and pneumothorax between the two groups. In the <30 mm group, there was no significant difference in the success rate of single puncture and the success rate of puncture between the two groups according to the size of the lesions. In the ≥30 mm group, the success rate of single puncture (97.1%) and puncture success rate (97.1%) in the contrast guidance group were higher than those in the conventional ultrasound guidance group (70.3%, 78.4%) and the difference was statistically significant ( < 0.05).
Compared with conventional ultrasound, for peripheral pulmonary lesions guided by contrast-enhanced ultrasonography, especially when the maximum diameter of the lesion is ≥ 30 mm, needle biopsy has better guiding significance; for peripheral lung lesions with a maximum diameter of <30 mm, contrast-enhanced ultrasonography is compared with conventional ultrasound guidance. The puncture success rate was not significantly different.
比较常规超声与超声造影引导经皮肺外周病灶穿刺活检的临床价值。
将 110 例肺外周病灶患者随机分为两组，即常规超声引导组和超声造影引导组，两组患者根据病灶大小进一步分为两组，对穿刺活检所取组织进行病理检查，将病理结果与术后病理结果及其他检查结果进行对比，同时记录并发症。
常规超声组单次穿刺成功率为 72.7%，穿刺成功率为 80.0%；超声造影组单次穿刺成功率为 90.9%，穿刺成功率为 94.6%。两组比较差异有统计学意义。两组均无明显针道出血及气胸发生。在病灶最大径<30 mm 组，两组间根据病灶大小比较单次穿刺成功率及穿刺成功率差异均无统计学意义；在病灶最大径≥30 mm 组，超声造影引导组单次穿刺成功率（97.1%）和穿刺成功率（97.1%）均高于常规超声引导组（70.3%，78.4%），差异均有统计学意义（ < 0.05）。
与常规超声比较，超声造影引导经皮肺外周病灶穿刺活检，尤其当病灶最大径≥30 mm 时，对穿刺活检有更好的指导意义；对于病灶最大径<30 mm 的肺外周病灶，超声造影引导与常规超声引导比较，穿刺成功率差异无统计学意义。
