慢性血液透析患者的血清及血细胞中的镍和锌

Serum and corpuscular nickel and zinc in chronic hemodialysis patients.

作者信息

Hosokawa S, Nishitani H, Umemura K, Tomoyoshi T, Sawanishi K, Yoshida O

出版信息

Nephron. 1987;45(2):151-3. doi: 10.1159/000184098.

Abstract

Serum and corpuscular nickel and zinc concentrations in 30 chronic hemodialysis patients were examined. Serum nickel and zinc levels before dialysis were 0.22 +/- 0.03 microgram/dl (normal value: 0.56 +/- 0.08 microgram/dl) and 70.0 +/- 13.4 micrograms/dl (normal value: 96 +/- 8 micrograms/dl) low, respectively. However, corpuscular nickel and zinc levels before dialysis were high: 1.25 +/- 0.24 microgram/dl (normal value: 0.88 +/- 0.17 microgram/dl) and 1,299 +/- 146 micrograms/dl (normal value: 1,120 +/- 80 micrograms/dl). Serum zinc levels significantly increased after dialysis, but serum nickel concentrations did not significantly increase during dialysis. Corpuscular nickel and zinc concentrations did not significantly change during dialysis.

摘要

检测了30例慢性血液透析患者的血清及血细胞中的镍和锌浓度。透析前血清镍和锌水平分别较低，为0.22±0.03微克/分升（正常值：0.56±0.08微克/分升）和70.0±13.4微克/分升（正常值：96±8微克/分升）。然而，透析前血细胞中的镍和锌水平较高：分别为1.25±0.24微克/分升（正常值：0.88±0.17微克/分升）和1299±146微克/分升（正常值：1120±80微克/分升）。透析后血清锌水平显著升高，但透析过程中血清镍浓度未显著升高。透析过程中血细胞中的镍和锌浓度未显著变化。