Department of Experimental Clinical and Health Psychology, Ghent University, Belgium.
Department of Experimental Clinical and Health Psychology, Ghent University, Belgium.
Biol Psychol. 2022 Jul;172:108358. doi: 10.1016/j.biopsycho.2022.108358. Epub 2022 May 23.
Previous event-related potential (ERP) research showed reduced self-referential processing in autism spectrum disorder (ASD). As different self-related stimuli were studied in isolation, it is unclear whether findings can be ascribed to a common underlying mechanism. Further, it is unknown whether altered self-referential processing is also evident in neurotypicals scoring high on ASD symptomatology. We compared ERPs in response to one's own name and face (versus other names/faces) between neurotypical adults scoring high versus low on ASD symptomatology. Conform previous research, the parietal P3 was enhanced, both for own name and face, indicating a self-referential effect. The N250 was only enhanced for one's own face. However, the self-referential parietal P3 effect did not correlate between the names and faces conditions, arguing against a common underlying mechanism. No group effects appeared, neither for names nor faces, suggesting that reduced self-referential processing is not a dimensional ASD feature in the neurotypical population.
先前的事件相关电位（ERP）研究表明，自闭症谱系障碍（ASD）患者的自我参照加工减少。由于不同的自我相关刺激是孤立研究的，因此尚不清楚这些发现是否可以归因于共同的潜在机制。此外，在自闭症症状评分较高的神经典型个体中，自我参照加工是否也发生改变尚不清楚。我们比较了自闭症症状评分较高和较低的神经典型成年人对自己的名字和面孔（与其他名字/面孔相比）的 ERP。与之前的研究一致，顶叶 P3 波在自身名字和面孔上都增强，表明存在自我参照效应。N250 波仅在自己的面孔上增强。然而，自身参照顶叶 P3 效应在名字和面孔条件之间没有相关性，这表明不存在共同的潜在机制。无论是名字还是面孔，都没有出现组间效应，这表明在神经典型人群中，自我参照加工减少并不是 ASD 的一个维度特征。
