Jadhav Charushila, Kamble Priti, Mundewadi Shafique, Jaiswal Nitesh, Mali Snehalata, Ranga Surbhi, Suvvari Tarun Kumar, Rukadikar Atul
Department of Physiology, All India Institute of Medical Sciences Gorakhpur, Uttar Pradesh, India.
Brihanmumbai Municipal Corporation Mumbai, India.
Int J Physiol Pathophysiol Pharmacol. 2022 Apr 15;14(2):73-83. eCollection 2022.
Electroencephalography is an excellent tool for assessing neurobiological and neurotransmission dysfunction. Event-related potentials (ERPs) are a simple, non-invasive method of studying neurophysiology. ERPs reflect complex activity of neural networks to blame for discriminative behavior of people and recognition of novel stimuli. They are defined as brain voltage fluctuations linked in time with some physical or mental event. EEG is used to assess ERPs, and its use has grown in popularity since the 1960s. This article provides an overview of the ERP methods as well as the properties of the various ERP components (contingent negative variation, namely wave P300, Bereitschafts potential, and mismatch negativity). It also describes ERP alterations linked with neurologic and psychiatric disorders and discusses the possibility of using this technique in experimental psychology. ERPs may reveal psychophysiological characteristics in obsessive compulsive disorder patients, which may have therapeutic and pharmacological consequences. The P3 wave is the most significant and researched component of the ERP record. It is divided into two parts: P3a and P3b. The P3 wave has therapeutic significance, in addition to its application in neurophysiological and psychophysiological research. One neurophysiology indicator of cognitive impairment in depression is the P300 component of the ERPs. The severity of the illness as well as sociodemographic disparities is likely to influence individuals with neurotic disorders' access to psychiatric care in the general community.
脑电图是评估神经生物学和神经传递功能障碍的优秀工具。事件相关电位(ERP)是研究神经生理学的一种简单、非侵入性方法。ERP反映神经网络的复杂活动,这种活动导致了人类的辨别行为和对新刺激的识别。它们被定义为与某些物理或心理事件在时间上相关联的脑电压波动。脑电图用于评估ERP,自20世纪60年代以来,其应用越来越广泛。本文概述了ERP方法以及各种ERP成分( contingent negative variation,即P300波、运动预备电位和失配负波)的特性。它还描述了与神经和精神疾病相关的ERP改变,并讨论了在实验心理学中使用该技术的可能性。ERP可能揭示强迫症患者的心理生理特征,这可能具有治疗和药理学意义。P3波是ERP记录中最重要且研究最多的成分。它分为两部分:P3a和P3b。P3波除了在神经生理学和心理生理学研究中的应用外,还具有治疗意义。抑郁症认知障碍的一个神经生理学指标是ERP中的P300成分。疾病的严重程度以及社会人口统计学差异可能会影响神经症患者在普通社区获得精神科护理的机会。