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Nat Rev Drug Discov. 2020 Sep;19(9):609-633. doi: 10.1038/s41573-020-0072-x. Epub 2020 Jul 24.
2
P300 development from infancy to adolescence.从婴儿期到青春期的 P300 发展。
Psychophysiology. 2020 Jul;57(7):e13346. doi: 10.1111/psyp.13346. Epub 2019 Feb 22.
3
EEG and ERP biomarkers of Alzheimer's disease: a critical review.阿尔茨海默病的 EEG 和 ERP 生物标志物:批判性综述。
Front Biosci (Landmark Ed). 2018 Jan 1;23(2):183-220. doi: 10.2741/4587.
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Driver Fatigue Classification With Independent Component by Entropy Rate Bound Minimization Analysis in an EEG-Based System.基于脑电图系统中通过熵率界最小化分析的独立成分进行驾驶员疲劳分类
IEEE J Biomed Health Inform. 2017 May;21(3):715-724. doi: 10.1109/JBHI.2016.2532354. Epub 2016 Feb 19.
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Reward anticipation and trait anhedonia: An electrophysiological investigation in subjects with schizophrenia.奖赏预期与特质性快感缺乏:对精神分裂症患者的一项电生理研究。
Clin Neurophysiol. 2016 Apr;127(4):2149-60. doi: 10.1016/j.clinph.2016.01.006. Epub 2016 Jan 22.
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Bereitschaftspotential in remitted paediatric bipolar disorder.缓解期儿童双相情感障碍的准备电位
Neurosci Lett. 2014 May 7;568:35-8. doi: 10.1016/j.neulet.2014.03.024. Epub 2014 Mar 26.
7
Can P300 distinguish among schizophrenia, schizoaffective and bipolar I disorders? An ERP study of response inhibition.P300 能否区分精神分裂症、分裂情感性障碍和双相情感障碍 I 型?一项关于反应抑制的 ERP 研究。
Schizophr Res. 2013 Dec;151(1-3):175-84. doi: 10.1016/j.schres.2013.10.020. Epub 2013 Nov 5.
8
[Psychophysiological characteristics of panic disorder and generalized anxiety disorder].[惊恐障碍和广泛性焦虑障碍的心理生理特征]
Zh Nevrol Psikhiatr Im S S Korsakova. 2013;113(5):11-4.
9
Bereitschaftspotential augmentation by neuro-feedback training in Parkinson's disease.神经反馈训练增强帕金森病的准备电位。
Clin Neurophysiol. 2013 Jul;124(7):1398-405. doi: 10.1016/j.clinph.2013.01.026. Epub 2013 Apr 12.
10
Positive emotion modulates cognitive control: an event-related potentials study.积极情绪调节认知控制:一项事件相关电位研究。
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脑电图作为一种用于精神疾病和神经症性障碍中事件相关电位的优秀工具的临床应用。

Clinical applications of EEG as an excellent tool for event related potentials in psychiatric and neurotic disorders.

作者信息

Jadhav Charushila, Kamble Priti, Mundewadi Shafique, Jaiswal Nitesh, Mali Snehalata, Ranga Surbhi, Suvvari Tarun Kumar, Rukadikar Atul

机构信息

Department of Physiology, All India Institute of Medical Sciences Gorakhpur, Uttar Pradesh, India.

Brihanmumbai Municipal Corporation Mumbai, India.

出版信息

Int J Physiol Pathophysiol Pharmacol. 2022 Apr 15;14(2):73-83. eCollection 2022.

PMID:35619664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9123476/
Abstract

Electroencephalography is an excellent tool for assessing neurobiological and neurotransmission dysfunction. Event-related potentials (ERPs) are a simple, non-invasive method of studying neurophysiology. ERPs reflect complex activity of neural networks to blame for discriminative behavior of people and recognition of novel stimuli. They are defined as brain voltage fluctuations linked in time with some physical or mental event. EEG is used to assess ERPs, and its use has grown in popularity since the 1960s. This article provides an overview of the ERP methods as well as the properties of the various ERP components (contingent negative variation, namely wave P300, Bereitschafts potential, and mismatch negativity). It also describes ERP alterations linked with neurologic and psychiatric disorders and discusses the possibility of using this technique in experimental psychology. ERPs may reveal psychophysiological characteristics in obsessive compulsive disorder patients, which may have therapeutic and pharmacological consequences. The P3 wave is the most significant and researched component of the ERP record. It is divided into two parts: P3a and P3b. The P3 wave has therapeutic significance, in addition to its application in neurophysiological and psychophysiological research. One neurophysiology indicator of cognitive impairment in depression is the P300 component of the ERPs. The severity of the illness as well as sociodemographic disparities is likely to influence individuals with neurotic disorders' access to psychiatric care in the general community.

摘要

脑电图是评估神经生物学和神经传递功能障碍的优秀工具。事件相关电位(ERP)是研究神经生理学的一种简单、非侵入性方法。ERP反映神经网络的复杂活动,这种活动导致了人类的辨别行为和对新刺激的识别。它们被定义为与某些物理或心理事件在时间上相关联的脑电压波动。脑电图用于评估ERP,自20世纪60年代以来,其应用越来越广泛。本文概述了ERP方法以及各种ERP成分( contingent negative variation,即P300波、运动预备电位和失配负波)的特性。它还描述了与神经和精神疾病相关的ERP改变,并讨论了在实验心理学中使用该技术的可能性。ERP可能揭示强迫症患者的心理生理特征,这可能具有治疗和药理学意义。P3波是ERP记录中最重要且研究最多的成分。它分为两部分:P3a和P3b。P3波除了在神经生理学和心理生理学研究中的应用外,还具有治疗意义。抑郁症认知障碍的一个神经生理学指标是ERP中的P300成分。疾病的严重程度以及社会人口统计学差异可能会影响神经症患者在普通社区获得精神科护理的机会。