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前房内注射甲氨蝶呤治疗上皮植入

Intracameral Injection of Methotrexate for Treatment of Epithelial Ingrowth.

作者信息

Salari Farhad, Fakhraie Ghasem, Asadi Amoli Fahimeh, Zarei-Ghanavati Mehran

机构信息

Department of Cornea, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Curr Ophthalmol. 2022 Apr 16;34(1):115-117. doi: 10.4103/JOCO.JOCO_159_21. eCollection 2022 Jan-Mar.

DOI:10.4103/JOCO.JOCO_159_21
PMID:35620380
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9128425/
Abstract

PURPOSE

To report a case of intracameral injection of methotrexate (MTX) to treat the epithelial ingrowth that occurred following glaucoma surgery.

METHODS

A case report of a 40-year-old male with epithelial ingrowth after implantation of Ahmed glaucoma valve.

RESULTS

The patient was treated with 11 doses of weekly intracameral MTX (400 mg/0.1 ml). Clinical evidence of recurrence was not observed after 11 months of follow-up.

DISCUSSION

Intracameral MTX can be used as an alternative for the treatment of epithelial ingrowth.

摘要

目的

报告1例前房内注射甲氨蝶呤（MTX）治疗青光眼手术后发生的上皮植入的病例。

方法

1例40岁男性患者植入艾哈迈德青光眼引流阀后发生上皮植入的病例报告。

结果

患者接受了11次每周1次的前房内MTX注射（400mg/0.1ml）。随访11个月后未观察到复发的临床证据。

讨论

前房内MTX可作为治疗上皮植入的一种替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf16/9128425/1b1ad50b2301/JCO-34-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf16/9128425/9fa031473990/JCO-34-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf16/9128425/1b1ad50b2301/JCO-34-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf16/9128425/9fa031473990/JCO-34-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf16/9128425/1b1ad50b2301/JCO-34-115-g002.jpg

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JAMA Ophthalmol. 2019 Sep 1;137(9):1082-1083. doi: 10.1001/jamaophthalmol.2019.2151.
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