Pittschieler K
Padiatr Padol. 1986;21(4):363-6.
In 16 children with coeliac disease consecutively diagnosed on the basis of 3 peroral small bowel biopsies in a period of 3 years 13 (81%) had low levels of folic acid in the serum (norm. reference range: 1.8-9 ng/ml) and in erythrocytes (norm. reference range: 150-450 ng/ml cells). The determination of folic acid has a better diagnostic value as the one-hour-D-Xylosetest. The low level of folic acid is the most constant nutritional deficiency in our group of coeliac patients. The determination of folate in the serum and erythrocytes is a highly sensitive screening and at the time it will indicate the adequate therapy.
在3年期间通过3次经口小肠活检连续确诊的16例乳糜泻患儿中，13例（81%）血清叶酸水平（正常参考范围：1.8 - 9 ng/ml）及红细胞叶酸水平（正常参考范围：150 - 450 ng/ml细胞）较低。叶酸测定比1小时D - 木糖试验具有更好的诊断价值。叶酸水平低是我们这组乳糜泻患者中最常见的营养缺乏情况。血清和红细胞中叶酸的测定是一种高度敏感的筛查方法，同时也能指示适当的治疗。
