Synthesis of 2'-deoxy-6,3'-methano-cyclo-pyrimidine nucleosides.
作者信息
Yoshimura Y, Sano T, Matsuda A, Ueda T
出版信息
Nucleic Acids Symp Ser. 1986(17):53-5.
PMID:3562275
Abstract
The nucleophilic attack of lithiated pyrimidines to a suitably-protected 3-ketosugar, afforded the 3-branched sugar stereospecifically, followed by intramolecular glycosylation to give 6,3'-methano-cyclo-pyrimidine nucleosides. The 2'-deoxygenation was achieved by sequential protection, deprotection and radical reduction.
摘要
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