采用分子内糖基化反应合成5'-脱氧-5'-取代嘧啶核苷
Synthesis of 5'-deoxy-5'-substituted pyrimidine nucleosides employing intramolecular glycosylation.
作者信息
Sugimura H, Kato Y
机构信息
Noguchi Institute, Tokyo, Japan.
出版信息
Nucleic Acids Symp Ser. 1997(37):49-50.
PMID:9585993
Abstract
5'-Deoxy-5'-arylthio and 5'-azido pyrimidine nucleosides were synthesized employing intramolecular glycosylation, in which a reaction intermediate was treated in situ with thiol and an azide salt, respectively.
摘要
采用分子内糖基化反应合成了5'-脱氧-5'-芳硫基和5'-叠氮基嘧啶核苷，其中反应中间体分别用硫醇和叠氮盐进行原位处理。
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