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新冠病毒疫苗接种的优先排序。“VALIDATE”方法的附加值。

Prioritization of COVID-19 vaccination. The added value of the "VALIDATE" approach.

机构信息

Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Rome, Italy.

Department for Health Evidence, Radboud University Medical Centre, Nijmegen, The Netherlands.

出版信息

Health Policy. 2022 Aug;126(8):770-776. doi: 10.1016/j.healthpol.2022.05.005. Epub 2022 May 20.

DOI:10.1016/j.healthpol.2022.05.005
PMID:35623910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9121636/
Abstract

Prioritization of COVID-19 vaccines is one of the most relevant topics in the current pandemic emergency. Prioritization decisions are political decisions that are value-laden, and as such of ethical nature. Despite the clear political and ethical nature of this topic, prioritization decisions are often interpreted and presented as scientific decisions. The aim of this article is twofold. First, we aim to show critical points that characterize certain pandemic vaccination plans from the ethical viewpoint using four dimensions (problem definitions, incorporation of different perspectives, context, and specification). The four dimensions were drawn from findings of the European project "VALIDATE" (VALues In Doing Assessments of healthcare TEchnologies", https://validatehta.eu). Second, we aim to reframe the issue about prioritization itself in the light of the four dimensions mentioned. Our conclusion is that policy-problem definitions, incorporation of different perspectives, contextual considerations and specification of moral principles seem to be common critical points of some vaccination plan documents. The European project "VALIDATE" seems to be able to provide a useful and profitable approach to address many of these critical points.

摘要

新冠病毒疫苗的优先排序是当前大流行紧急情况下最相关的话题之一。优先排序决策是政治性的,且充满价值判断,因此具有伦理性质。尽管这个话题具有明显的政治性和伦理性,但优先排序决策往往被解释和呈现为科学决策。本文的目的有两个。首先,我们旨在使用四个维度(问题定义、不同观点的纳入、背景和具体说明)从伦理角度展示某些大流行疫苗接种计划的特征要点。这四个维度是从欧洲项目“VALIDATE”(评估医疗保健技术的价值观,https://validatehta.eu)的研究结果中得出的。其次,我们旨在根据上述四个维度重新构建关于优先排序本身的问题。我们的结论是,政策问题定义、不同观点的纳入、背景因素的考虑以及道德原则的具体说明似乎是一些疫苗接种计划文件的常见要点。欧洲项目“VALIDATE”似乎能够为解决许多这些要点提供一个有用且有利的方法。

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COVID-19 vaccine challenges: What have we learned so far and what remains to be done?COVID-19 疫苗面临的挑战:到目前为止我们了解到了什么,还有什么需要做?
Health Policy. 2021 May;125(5):553-567. doi: 10.1016/j.healthpol.2021.03.013. Epub 2021 Mar 26.
3
Who should be prioritized for COVID-19 vaccination in China? A descriptive study.在中国,谁应该优先接种 COVID-19 疫苗?一项描述性研究。
BMC Med. 2021 Feb 10;19(1):45. doi: 10.1186/s12916-021-01923-8.
4
Queue questions: Ethics of COVID-19 vaccine prioritization.排队提问:新冠病毒疫苗优先排序的伦理问题。
Bioethics. 2021 May;35(4):348-355. doi: 10.1111/bioe.12858. Epub 2021 Feb 8.
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How should we conduct pandemic vaccination?我们应该如何开展大流行疫苗接种?
Vaccine. 2021 Feb 5;39(6):994-999. doi: 10.1016/j.vaccine.2020.12.059. Epub 2021 Jan 8.
6
A global agenda for older adult immunization in the COVID-19 era: A roadmap for action.老龄化人口在新冠疫情时代的免疫接种全球议程:行动路线图。
Vaccine. 2021 Aug 31;39(37):5240-5250. doi: 10.1016/j.vaccine.2020.06.082. Epub 2020 Jul 3.
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Value Health. 2020 Jun;23(6):824-825. doi: 10.1016/j.jval.2020.05.001.
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12 Lessons learned from the management of the coronavirus pandemic.从冠状病毒大流行管理中吸取的 12 点经验教训。
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Prioritising access to pandemic influenza vaccine: a review of the ethics literature.优先获得大流行性流感疫苗:对伦理文献的回顾。
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PLoS One. 2017 Aug 30;12(8):e0182720. doi: 10.1371/journal.pone.0182720. eCollection 2017.