Ventrucci M, Pezzilli R, Naldoni P, Montone L, Gullo L
Pancreas. 1986;1(4):320-3. doi: 10.1097/00006676-198607000-00005.
In 134 consecutive patients with acute abdominal pain, we evaluated the clinical role of a new rapid test for serum lipase based on latex agglutination. The results were compared with those obtained with a widely used lipase immunoassay as well as with serum amylase and pancreatic isoamylase measurements. Fifty-five healthy subjects were studied as controls. In 174 cases (121 patients and 53 controls) the results of the two lipase assays were in agreement. A positive lipase latex test was found in 10 of 12 patients with acute pancreatitis, in eight of 24 patients with other pancreatic diseases, and in 14 of 98 with nonpancreatic diseases. The sensitivity and specificity of this test were similar to those of the other pancreatic enzyme assays performed. The results indicate that the lipase latex agglutination test is useful for emergency screening for acute pancreatitis in patients with acute abdominal pain.
在134例连续的急性腹痛患者中，我们评估了一种基于乳胶凝集的新型血清脂肪酶快速检测方法的临床作用。将结果与广泛使用的脂肪酶免疫测定法以及血清淀粉酶和胰淀粉酶测量结果进行比较。研究了55名健康受试者作为对照。在174例病例（121例患者和53例对照）中，两种脂肪酶检测结果一致。在12例急性胰腺炎患者中有10例、24例其他胰腺疾病患者中有8例以及98例非胰腺疾病患者中有14例脂肪酶乳胶试验呈阳性。该检测方法的敏感性和特异性与所进行的其他胰腺酶检测相似。结果表明，脂肪酶乳胶凝集试验有助于对急性腹痛患者进行急性胰腺炎的急诊筛查。
