Li Yuan, Wang Mei-Yi, Xu Meng, Xie Wen-Ting, Zhang Yu-Ming, Yang Xi-Yue, Wang Zhi-Xin, Song Rui, Yang Liu, Ma Jin-Ping, Zhang Jia, Han Chen-Xiao, Wang Cheng-Zhi, Liu Wan-Ying, Gan Wan-Hong, Su Rui, Ma Hai-Lin, Li Hao
Plateau Brain Science Research Center, Tibet University/South China Normal University, Lhasa 850012, China.
Center on Aging Psychology, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing 100101, China.
Brain Sci. 2022 Apr 29;12(5):585. doi: 10.3390/brainsci12050585.
High-altitude exposure can negatively impact one’s ability to accurately perceive time. This study focuses on Chinese migrants who have traveled to the Tibetan plateau and explores the effects of high-altitude exposure on their time interval judgment abilities based on three separate studies. In Study 1, it was found that exposure to high altitudes negatively impacted the time interval judgment functions of the migrants compared with a low-altitude control group; they exhibited a prolonged response time (540 ms: p = 0.006, 95% CI (−1.70 −0.32)) and reduced accuracy (1080 ms: p = 0.032, 95% CI (0.06 1.26)) in certain behavioral tasks. In Study 2, the results showed that high-altitude exposure and sleepiness had an interactive effect on time interval judgment (1080 ms) (p < 0.05, 95% CI (−0.83 −0.40)). To further verify our interaction hypothesis, in Study 3, we investigated the time interval judgment of interactions between acute high-altitude exposure and sleepiness level. The results revealed that the adaptation effect disappeared and sleepiness significantly exacerbated the negative effects of high-altitude exposure on time interval judgment (p < 0.001, 95% CI (−0.85 −0.34)). This study is the first to examine the effects of high-altitude exposure on time interval judgment processing functions and the effects of sleep-related factors on individual time interval judgment.
高原暴露会对人准确感知时间的能力产生负面影响。本研究聚焦于前往青藏高原的中国移民，并基于三项独立研究探讨高原暴露对他们时间间隔判断能力的影响。在研究1中，发现与低海拔对照组相比，高原暴露对移民的时间间隔判断功能产生了负面影响；在某些行为任务中，他们表现出反应时间延长（540毫秒：p = 0.006，95%置信区间（-1.70 -0.32））和准确性降低（1080毫秒：p = 0.032，95%置信区间（0.06 1.26））。在研究2中，结果表明高原暴露和困倦对时间间隔判断（1080毫秒）有交互作用（p < 0.05，95%置信区间（-0.83 -0.40））。为了进一步验证我们的交互作用假设，在研究3中，我们调查了急性高原暴露与困倦程度之间相互作用的时间间隔判断。结果显示适应效应消失，困倦显著加剧了高原暴露对时间间隔判断的负面影响（p < 0.001，95%置信区间（-0.85 -0.34））。本研究首次考察了高原暴露对时间间隔判断加工功能的影响以及睡眠相关因素对个体时间间隔判断的影响。
