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新冠康复诊所患者睡眠质量与心理健康之间的关联

Association between Sleep Quality and Mental Health among Patients at a Post-COVID-19 Recovery Clinic.

作者信息

Nowakowski Sara, Kokonda Manasa, Sultana Rizwana, Duong Brittany B, Nagy Sarah E, Zaidan Mohammed F, Baig Mirza M, Grigg Bryan V, Seashore Justin, Deer Rachel R

机构信息

Department of Medicine, Baylor College of Medicine, Houston, TX 77021, USA.

Center of Innovation in Quality, Effectiveness & Safety, Michael E DeBakey Veterans Association, Houston, TX 77021, USA.

出版信息

Brain Sci. 2022 Apr 30;12(5):586. doi: 10.3390/brainsci12050586.

Abstract

A growing body of research documents the persistence of physical and neuropsychiatric symptoms following the resolution of acute COVID-19 infection. To the best of our knowledge, no published study has examined the interaction between insomnia and mental health. Accordingly, we proposed to examine new diagnoses of insomnia, and referrals to pulmonary and sleep medicine clinics for treatment of sleep disorders, in patients presenting to one post-acute COVID-19 recovery clinic. Additionally, we aimed to examine the relationship between poor sleep quality, depression, anxiety, and post-traumatic stress. Patients presented to the clinic on average 2 months following COVID-19 infection; 51.9% ( = 41) were hospitalized, 11.4% ( 9) were in the intensive care unit, 2.5% ( 2) were on a mechanical ventilator, and 38.0% ( 30) were discharged on oxygen. The most commonly reported symptom was fatigue (88%, = 70), with worse sleep following a COVID-19 infection reported in 50.6% ( = 40). The mean PSQI score was 9.7 (82.3%, = 65 with poor sleep quality). The mean GAD-7 score was 8.3 (22.8%, 14 with severe depression). The mean PHQ-9 was 10.1 (17.8%, 18 with severe anxiety). The mean IES-6 was 2.1 (54.4%, 43 with post-traumatic stress). Poor sleep quality was significantly associated with increased severity of depression, anxiety, and post-traumatic stress. Future work should follow patients longitudinally to examine if sleep, fatigue, and mental health symptoms improve over time.

摘要

越来越多的研究记录了急性新冠病毒感染康复后身体和神经精神症状的持续存在。据我们所知,尚未有已发表的研究探讨失眠与心理健康之间的相互作用。因此,我们建议对一家新冠病毒感染后康复诊所的患者进行检查,以确定失眠的新诊断情况,以及转介至肺病和睡眠医学诊所治疗睡眠障碍的情况。此外,我们旨在研究睡眠质量差、抑郁、焦虑和创伤后应激之间的关系。患者在新冠病毒感染后平均2个月到诊所就诊;51.9%(n = 41)曾住院,11.4%(n = 9)曾入住重症监护病房,2.5%(n = 2)曾使用机械通气,38.0%(n = 30)出院时仍需吸氧。最常报告的症状是疲劳(88%,n = 70),50.6%(n = 40)的患者报告新冠病毒感染后睡眠变差。匹兹堡睡眠质量指数(PSQI)平均得分为9.7(82.3%,n = 65睡眠质量差)。广泛性焦虑障碍量表(GAD - 7)平均得分为8.3(22.8%,n = 14重度抑郁)。患者健康问卷-9(PHQ - 9)平均得分为10.1(17.8%,n = 18重度焦虑)。创伤后应激障碍自评量表(IES - 6)平均得分为2.1(54.4%,n = 43有创伤后应激)。睡眠质量差与抑郁、焦虑和创伤后应激的严重程度增加显著相关。未来的研究应纵向跟踪患者,以检查睡眠、疲劳和精神健康症状是否会随着时间推移而改善。

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