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The Challenge Arising from New Knowledge about Immune and Inflammatory Skin Diseases: Where We Are Today and Where We Are Going.免疫和炎症性皮肤病新知识带来的挑战：我们的现状与未来走向
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2
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[Clinical features of imbalance between Th1 and Th22 cells and its association with disease progression in patients with liver cirrhosis].[肝硬化患者Th1与Th22细胞失衡的临床特征及其与疾病进展的关系]
Zhonghua Gan Zang Bing Za Zhi. 2017 Oct 20;25(10):738-744. doi: 10.3760/cma.j.issn.1007-3418.2017.10.004.
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Severe atopic dermatitis is characterized by selective expansion of circulating TH2/TC2 and TH22/TC22, but not TH17/TC17, cells within the skin-homing T-cell population.严重特应性皮炎的特征是循环中 TH2/TC2 和 TH22/TC22 细胞而非 TH17/TC17 细胞的选择性扩增，这些细胞存在于皮肤归巢 T 细胞群中。
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Medroxyprogesterone Acetate Decreases Th1, Th17, and Increases Th22 Responses via AHR Signaling Which Could Affect Susceptibility to Infections and Inflammatory Disease.醋酸甲羟孕酮通过 AHR 信号降低 Th1、Th17，增加 Th22 反应，这可能影响感染和炎症性疾病的易感性。
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Elevated frequencies of circulating Th22 cell in addition to Th17 cell and Th17/Th1 cell in patients with acute coronary syndrome.急性冠状动脉综合征患者循环中Th22细胞以及Th17细胞和Th17/Th1细胞的频率升高。
PLoS One. 2013 Dec 3;8(12):e71466. doi: 10.1371/journal.pone.0071466. eCollection 2013.
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[Immune state of Th1, Th2 and Th17 subpopulation in experimental autoimmune myocarditis].[实验性自身免疫性心肌炎中Th1、Th2和Th17亚群的免疫状态]
Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Nov;42(6):751-6.

引用本文的文献

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Teledermatology for Common Inflammatory Skin Conditions: The Medicine of the Future?常见炎症性皮肤病的远程皮肤病学：未来医学？
Life (Basel). 2023 Apr 18;13(4):1037. doi: 10.3390/life13041037.
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The Role of Teledermatology During the COVID-19 Pandemic: A Narrative Review.远程皮肤病学在2019年冠状病毒病大流行期间的作用：一项叙述性综述
Clin Cosmet Investig Dermatol. 2022 Dec 19;15:2785-2793. doi: 10.2147/CCID.S377029. eCollection 2022.

本文引用的文献

1
Paradoxical Hidradenitis Suppurativa during Biologic Therapy, an Emerging Challenge: A Systematic Review.生物治疗期间的反常性化脓性汗腺炎：一项新出现的挑战——系统评价
Biomedicines. 2022 Feb 16;10(2):455. doi: 10.3390/biomedicines10020455.
2
Novel Therapeutic Approaches to Psoriasis and Risk of Infectious Disease.银屑病的新型治疗方法与传染病风险
Biomedicines. 2022 Jan 21;10(2):228. doi: 10.3390/biomedicines10020228.
3
Systemic Sclerosis: From Pathophysiology to Novel Therapeutic Approaches.系统性硬化症：从病理生理学到新型治疗方法
Biomedicines. 2022 Jan 12;10(1):163. doi: 10.3390/biomedicines10010163.
4
Thalidomide Exerts Anti-Inflammatory Effects in Cutaneous Lupus by Inhibiting the IRF4/NF-ҡB and AMPK1/mTOR Pathways.沙利度胺通过抑制IRF4/NF-ҡB和AMPK1/mTOR信号通路发挥对皮肤型红斑狼疮的抗炎作用。
Biomedicines. 2021 Dec 7;9(12):1857. doi: 10.3390/biomedicines9121857.
5
Pustular Psoriasis: From Pathophysiology to Treatment.脓疱型银屑病：从病理生理学到治疗
Biomedicines. 2021 Nov 23;9(12):1746. doi: 10.3390/biomedicines9121746.
6
Repeated α-GalCer Administration Induces a Type 2 Cytokine-Biased iNKT Cell Response and Exacerbates Atopic Skin Inflammation in Vα14 NC/Nga Mice.重复给予α-半乳糖神经酰胺可诱导2型细胞因子偏向性的不变自然杀伤T细胞反应，并加剧Vα14 NC/Nga小鼠的特应性皮炎。
Biomedicines. 2021 Nov 4;9(11):1619. doi: 10.3390/biomedicines9111619.
7
Immunological Targets of Biologic Drugs in Allergic Skin Diseases in Children.儿童过敏性皮肤病中生物药物的免疫靶点
Biomedicines. 2021 Nov 4;9(11):1615. doi: 10.3390/biomedicines9111615.
8
Neoplastic Implications in Patients Suffering from Hidradenitis Suppurativa under Systemic Treatments.全身性治疗的化脓性汗腺炎患者的肿瘤学意义
Biomedicines. 2021 Nov 1;9(11):1594. doi: 10.3390/biomedicines9111594.
9
Psoriasis as an Immune-Mediated and Inflammatory Systemic Disease: From Pathophysiology to Novel Therapeutic Approaches.银屑病作为一种免疫介导的炎症性全身性疾病：从病理生理学到新型治疗方法
Biomedicines. 2021 Oct 21;9(11):1511. doi: 10.3390/biomedicines9111511.
10
New-Onset Psoriatic Arthritis under Biologics in Psoriasis Patients: An Increasing Challenge?银屑病患者使用生物制剂时新发银屑病关节炎：挑战日益增加？
Biomedicines. 2021 Oct 15;9(10):1482. doi: 10.3390/biomedicines9101482.

免疫和炎症性皮肤病新知识带来的挑战：我们的现状与未来走向

The Challenge Arising from New Knowledge about Immune and Inflammatory Skin Diseases: Where We Are Today and Where We Are Going.

作者信息

Campanati Anna, Martina Emanuela, Offidani Annamaria

机构信息

Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60020 Ancona, Italy.

出版信息

Biomedicines. 2022 Apr 20;10(5):950. doi: 10.3390/biomedicines10050950.

DOI:10.3390/biomedicines10050950
PMID:35625686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9138773/
Abstract

Skin is the widest and most accessible organ of the human body, and among its functions, the immunological one has been one of the most intriguing and investigated during the last 10 years; so, inflammatory and immune-mediated skin diseases (s-IMID) are considered as useful models to understand which physiopathological pathways are implicated in Th1, Th2, Th17, and Th22 inflammatory diseases [...].

摘要

皮肤是人体最大且最易接触到的器官，在其诸多功能中，免疫功能在过去十年一直是最引人关注且研究最多的功能之一；因此，炎症性和免疫介导的皮肤病（s-IMID）被视为了解Th1、Th2、Th17和Th22炎症性疾病涉及哪些生理病理途径的有用模型[...]。