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脂肪瘤性肿瘤:MRI报告诊断与组织学诊断的比较

Lipomatous Tumors: A Comparison of MRI-Reported Diagnosis with Histological Diagnosis.

作者信息

Ballhause Tobias M, Korthaus Alexander, Jahnke Martin, Frosch Karl-Heinz, Yamamura Jin, Dust Tobias, Schlickewei Carsten W, Priemel Matthias H

机构信息

Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Department of Trauma Surgery, Orthopedics and Sports Traumatology, BG Hospital Hamburg, 21033 Hamburg, Germany.

出版信息

Diagnostics (Basel). 2022 May 21;12(5):1281. doi: 10.3390/diagnostics12051281.

Abstract

Lipomatous tumors are among the most common soft tissue tumors (STTs). Magnetic resonance imaging (MRI) is a state-of-the-art diagnostic tool used to differentiate and characterize STTs. Radiological misjudgment can lead to incorrect treatment. This was a single-center retrospective study. Two hundred and forty lipomatous tumors were included. MRI diagnoses were categorized as benign, intermediate, or malignant and were compared with histological diagnoses. Tumor volumes were measured by MRI and from surgical specimens. The tumor was correctly categorized 73.3% of the time. A total of 21.7% of tumors were categorized as more malignant in MRI reports than they were by histology, and vice versa for 5.0% of tumors. Volume measured by MRI was not different from actual tumor size in pathology. Atypical lipomatous tumors (ALTs) and liposarcomas (LPSs) were larger when compared with lipomata and occurred in older patients. Based on the MRI-suspected tumor entity, surgical treatment can be planned. Large lipomatous tumors in elderly patients are more likely to be ALTs. However, a safe threshold size or volume for ALTs cannot be determined.

摘要

脂肪瘤是最常见的软组织肿瘤(STT)之一。磁共振成像(MRI)是用于鉴别和表征软组织肿瘤的先进诊断工具。放射学误诊会导致治疗不当。这是一项单中心回顾性研究。纳入了240例脂肪瘤。MRI诊断分为良性、中间型或恶性,并与组织学诊断进行比较。通过MRI和手术标本测量肿瘤体积。肿瘤在73.3%的时间里被正确分类。共有21.7%的肿瘤在MRI报告中的恶性程度分类高于组织学诊断结果,反之,5.0%的肿瘤则相反。MRI测量的体积与病理中实际肿瘤大小无差异。与脂肪瘤相比,非典型脂肪瘤(ALT)和脂肪肉瘤(LPS)更大,且发生在老年患者中。基于MRI怀疑的肿瘤类型,可以规划手术治疗。老年患者中的大型脂肪瘤更可能是ALT。然而,无法确定ALT的安全阈值大小或体积。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f4f/9141562/191a2e69c29e/diagnostics-12-01281-g001.jpg

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