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用于治疗脑瘫患儿“高危髋关节”的股骨近端引导生长——一项系统评价

Guided Growth of the Proximal Femur for the Management of the 'Hip at Risk' in Children with Cerebral Palsy-A Systematic Review.

作者信息

Lebe Moritz, van Stralen Renée Anne, Buddhdev Pranai

机构信息

Broomfield & Addenbrookes Hospitals, Chelmsford CM1 7ET, UK.

Erasmus MC Sophia Children's Hospital, 3015 CN Rotterdam, The Netherlands.

出版信息

Children (Basel). 2022 Apr 25;9(5):609. doi: 10.3390/children9050609.

Abstract

BACKGROUND

Guided growth is frequently used to modify lower-limb alignment in children, and recently temporary medial hemiepiphysiodesis of the proximal femur (TMH-PF) has been used for the management of hips at risk of subluxation in cerebral palsy (CP) patients. The aim of our study was to evaluate the efficacy of TMH-PF in the management of neuromuscular hip dysplasia in children with cerebral palsy.

METHODS

A systematic search of the literature was performed by using PubMed, EMBASE, CINAHL, MEDLINE, Scopus and Cochrane databases. Pre- and postoperative radiographic changes of the migration percentage (MP), head-shaft angle (HSA) and acetabular index (AI) were included in a meta-analysis. Secondary outcomes were treatment complication rates, technical considerations and the limitations of this novel technique.

RESULTS

Four studies (93 patients; 178 hips) met the eligibility criteria for inclusion in the meta-analysis. All three radiographic measurements showed significant changes at a minimum of 2 years of follow-up. Mean changes for MP were 8.48% (95% CI 3.81-13.14), HSA 12.28° (95% CI 11.17-13.39) and AI 3.41° (95% CI 0.72-6.10), with I of 75.74%, 0% and 87.68%, respectively. The serious complication rate was overall low; however, physeal 'growing off' of the screw was reported in up to 43% of hips treated.

CONCLUSION

TMH-PF is an effective and predictable method to treat CP patients with 'hips at risk', and the overall complication rate is low; however, further work is required to identify the best candidates and surgical timing, as well as choice of technique and implant.

摘要

背景

引导生长常用于儿童下肢对线的矫正,最近股骨近端临时内侧半骨骺阻滞术(TMH-PF)已被用于治疗脑瘫(CP)患者有半脱位风险的髋关节。我们研究的目的是评估TMH-PF在治疗脑瘫儿童神经肌肉性髋关节发育不良中的疗效。

方法

通过使用PubMed、EMBASE、CINAHL、MEDLINE、Scopus和Cochrane数据库对文献进行系统检索。将术前和术后的影像学变化,即迁移百分比(MP)、头干角(HSA)和髋臼指数(AI)纳入荟萃分析。次要结果包括治疗并发症发生率、技术考量以及这项新技术的局限性。

结果

四项研究(93例患者;178个髋关节)符合纳入荟萃分析的资格标准。所有三项影像学测量在至少2年的随访中均显示出显著变化。MP的平均变化为8.48%(95%CI 3.81 - 13.14),HSA为12.28°(95%CI 11.17 - 13.39),AI为3.41°(95%CI 0.72 - 6.10),I分别为75.74%、0%和87.68%。严重并发症发生率总体较低;然而,报道称在接受治疗的髋关节中,高达43%出现螺钉“骨骺脱离”。

结论

TMH-PF是治疗有“髋关节风险”的CP患者的一种有效且可预测的方法,总体并发症发生率较低;然而,需要进一步研究以确定最佳候选者、手术时机,以及技术和植入物的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d889/9140189/4da0c2af268c/children-09-00609-g001.jpg

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