Department of Neurosurgery, Yonsei University Wonju College of Medicine, Wonju 26426, Korea.
Department of Medicine, Graduate School, Yonsei University Wonju College of Medicine, Wonju 26426, Korea.
Int J Environ Res Public Health. 2022 May 18;19(10):6140. doi: 10.3390/ijerph19106140.
Obesity and overweight status are primary risk factors for stroke. A relative small number of studies has analyzed the association of abdominal obesity, a crucial indicator for insulin resistance with stroke, compared to general obesity. We aimed to reveal 31,490 records from the Korea National Health and Nutrition Examination Survey (KNHANES). Logistic regression was used to identify the association of abdominal obesity with the risk of stroke. For the multivariate model, covariates were determined based on the cardio-cerebro vascular prediction models. In the sex-specific multivariate logistic regression analysis (including age, antihypertensive drug, diabetes, current smoking, and systolic blood pressure as confounders), the elevated waist circumference (WC) in women was significantly associated with the increased risk for stroke. In case of the categorized form of WC, we discerned the non-linear relationships between WC and the stroke status. The sex-specific associations between the abdominal obesity and stroke status were shown and their relationship pattern exhibited non-linear relationships.
肥胖和超重是中风的主要危险因素。与一般肥胖相比,只有少数研究分析了腹部肥胖作为胰岛素抵抗的一个关键指标与中风的关系。我们的目的是从韩国国家健康和营养检查调查(KNHANES)中揭示 31490 条记录。使用逻辑回归来确定腹部肥胖与中风风险之间的关联。对于多变量模型,根据心血管预测模型确定协变量。在性别特异性多变量逻辑回归分析(包括年龄、抗高血压药物、糖尿病、当前吸烟和收缩压作为混杂因素)中,女性腰围(WC)升高与中风风险增加显著相关。在 WC 的分类形式中,我们发现 WC 与中风状态之间存在非线性关系。显示了腹部肥胖与中风状态之间的性别特异性关联,其关系模式表现出非线性关系。