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南非接受抗逆转录病毒治疗的 15 岁及以上艾滋病毒感染者和成人中是否存在风险补偿?2017 年全国艾滋病毒流行率、发病率、行为和传播调查的结果。

Is There Risk Compensation among HIV Infected Youth and Adults 15 Years and Older on Antiretroviral Treatment in South Africa? Findings from the 2017 National HIV Prevalence, Incidence, Behaviour and Communication Survey.

机构信息

Human Sciences Research Council, Cape Town 8000, South Africa.

Department of Psychology, University of Pretoria, Pretoria 0028, South Africa.

出版信息

Int J Environ Res Public Health. 2022 May 18;19(10):6156. doi: 10.3390/ijerph19106156.

DOI:10.3390/ijerph19106156
PMID:35627693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9141949/
Abstract

In this paper, risk compensation among individuals on antiretroviral therapy (ART), using the 2017 South African national survey on HIV, is explored. A multi-stage stratified cluster random sampling approach was used to realize 11,130 participants 15 years and older. Logistic regression analysis assessed the association between multiple sexual partners, condom use at last sexual encounter, consistency of condom usage and potential explanatory variables using HIV status and ART exposure as a mediator variable. HIV positive participants who were aware and on ART were less likely to have multiple sexual partners, and less likely not to use a condom at last sex compared to HIV positive participants who were aware but not on ART. The odds of reporting multiple sexual partners were significantly lower among older age groups, females, non-Black Africans, and rural settings, and higher among those with tertiary level education, and risky alcohol users. The odds of no condom use at last sexual encounter were more likely among older age groups, females, other race groups, and less likely among those with secondary level education. The odds of inconsistent condom use were more likely among older age groups, females, and other race groups, and less likely among those with tertiary level education, high risk and hazardous alcohol users. Risk compensation is not apparent among HIV infected adults who are on ART. Risk groups that should receive tailored interventions to reduced risky sexual behaviours were identified.

摘要

本文利用 2017 年南非全国艾滋病毒调查数据,探讨了接受抗逆转录病毒疗法(ART)的个体之间的风险补偿现象。采用多阶段分层聚类随机抽样方法,共纳入了 11130 名 15 岁及以上的参与者。使用逻辑回归分析评估了具有多个性伴侣、上次性行为时使用安全套、安全套使用一致性与潜在解释变量之间的关联,其中 HIV 状态和 ART 暴露作为中介变量。与知晓 HIV 感染但未接受 ART 的患者相比,知晓 HIV 感染且正在接受 ART 的患者更不可能有多个性伴侣,且在上次性行为时更不可能不使用安全套。在年龄较大、女性、非非洲裔黑人以及农村地区的参与者中,报告具有多个性伴侣的可能性显著降低,而在具有高等教育程度和高危饮酒者中,报告具有多个性伴侣的可能性更高。在年龄较大、女性、其他种族群体以及具有中等教育程度的参与者中,在上次性行为时不使用安全套的可能性更高。在年龄较大、女性以及其他种族群体中,报告安全套使用不一致的可能性更高,而在具有高等教育程度、高风险和有害饮酒者中,报告安全套使用不一致的可能性更低。接受 ART 的 HIV 感染成年人中,风险补偿并不明显。确定了应针对特定风险群体采取干预措施,以减少危险的性行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/9141949/aad5b84562da/ijerph-19-06156-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/9141949/0b3be7aee4ac/ijerph-19-06156-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/9141949/4439a8fd1c02/ijerph-19-06156-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/9141949/aad5b84562da/ijerph-19-06156-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/9141949/0b3be7aee4ac/ijerph-19-06156-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/9141949/4439a8fd1c02/ijerph-19-06156-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/9141949/aad5b84562da/ijerph-19-06156-g003.jpg

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3
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