• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新冠病毒感染期间耳鼻喉(ENT)症状的频率和严重程度。

Frequency and Severity of Ear-Nose-Throat (ENT) Symptoms during COVID-19 Infection.

机构信息

Department of Otorhinolaryngology and Laryngological Oncology in Zabrze, Medical University of Silesia, 41-800 Zabrze, Poland.

Student Society Affiliated with the Department of Otorhinolaryngology and Laryngological Oncology in Zabrze, Medical University of Silesia, 41-800 Zabrze, Poland.

出版信息

Medicina (Kaunas). 2022 Apr 29;58(5):623. doi: 10.3390/medicina58050623.

DOI:10.3390/medicina58050623
PMID:35630040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9143391/
Abstract

Background and Objectives: Coronavirus disease 2019 (COVID-19) is a new disease entity caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The main symptoms of infection at the onset of the pandemic include dyspnea, cough and high fever. Ear−nose−throat (ENT) symptoms are among the ones presented by patients in the course of infection. The aim of the study was to analyze the frequency of ENT symptoms and to assess their severity and duration in COVID-19 patients. Materials and Methods: The study included 337 patients who had been infected with SARS-CoV-2, as confirmed by a PCR test. The study participants were >18 years old; the mean age was 43.98 years ± 13.47 SD. The convalescents completed a questionnaire that contained 26 questions, including 9 detailed questions related to ENT symptoms, such as sore throat, vertigo, dizziness, hearing disorders, olfactory disorders, taste disturbance, headache, cough and dyspnea. The severity of symptoms was assessed using a Visual Analogue Scale (VAS). Results: The most reported ENT symptoms were olfactory disorders, which occurred in 72% of patients. The second most frequent symptom was taste disturbance (68%), VAS = 6.79 ± 3.01. Vertigo and dizziness were reported by 34% of respondents (VAS = 4.01 ± 2.01). Tinnitus was observed in 15% of patients, VAS = 3.87 ± 1.98; 14% of the subjects reported hearing impairment (VAS = 3.81 ± 2.37). Conclusions: Symptoms related to the sense of smell, taste and hearing are some of the most common symptoms in the course of COVID-19, which is important in the therapeutic and epidemiological management of patients. Delayed diagnosis and treatment of symptoms, especially those related to the hearing organ, may result in greater permanent damage.

摘要

背景和目的

新型冠状病毒病(COVID-19)是由严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)引起的新疾病实体。大流行初期感染的主要症状包括呼吸困难、咳嗽和高热。耳鼻喉(ENT)症状是患者在感染过程中出现的症状之一。本研究旨在分析 ENT 症状的频率,并评估 COVID-19 患者 ENT 症状的严重程度和持续时间。

材料和方法

本研究包括 337 名经 PCR 检测确诊感染 SARS-CoV-2 的患者。研究参与者年龄>18 岁,平均年龄为 43.98 岁±13.47 岁。康复者完成了一份包含 26 个问题的问卷,其中 9 个问题与 ENT 症状有关,如咽痛、眩晕、头晕、听力障碍、嗅觉障碍、味觉障碍、头痛、咳嗽和呼吸困难。症状的严重程度使用视觉模拟量表(VAS)进行评估。

结果

报告的 ENT 症状最常见的是嗅觉障碍,72%的患者出现嗅觉障碍。其次是味觉障碍(68%),VAS=6.79±3.01。34%的患者报告眩晕和头晕(VAS=4.01±2.01)。15%的患者出现耳鸣,VAS=3.87±1.98;14%的患者报告听力障碍(VAS=3.81±2.37)。

结论

与嗅觉、味觉和听力相关的症状是 COVID-19 病程中最常见的症状之一,这对于患者的治疗和流行病学管理很重要。症状,尤其是与听觉器官相关的症状的延迟诊断和治疗可能导致更大的永久性损害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/f4ddeb4475c5/medicina-58-00623-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/8bc987523f3c/medicina-58-00623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/c661fdf472cb/medicina-58-00623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/c91ccfb43c4d/medicina-58-00623-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/f4ddeb4475c5/medicina-58-00623-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/8bc987523f3c/medicina-58-00623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/c661fdf472cb/medicina-58-00623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/c91ccfb43c4d/medicina-58-00623-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db68/9143391/f4ddeb4475c5/medicina-58-00623-g004.jpg

相似文献

1
Frequency and Severity of Ear-Nose-Throat (ENT) Symptoms during COVID-19 Infection.新冠病毒感染期间耳鼻喉(ENT)症状的频率和严重程度。
Medicina (Kaunas). 2022 Apr 29;58(5):623. doi: 10.3390/medicina58050623.
2
Ear nose throat-related symptoms with a focus on loss of smell and/or taste in COVID-19 patients.新冠病毒感染者的耳鼻喉相关症状,重点是嗅觉和/或味觉丧失。
Am J Otolaryngol. 2020 Nov-Dec;41(6):102622. doi: 10.1016/j.amjoto.2020.102622. Epub 2020 Jun 23.
3
Correlation of ENT Symptoms with Age, Sex, and Anti-SARS-CoV-2 Antibody Titer in Plasma.耳鼻喉症状与年龄、性别及血浆中抗SARS-CoV-2抗体滴度的相关性
J Clin Med. 2023 Jan 12;12(2):610. doi: 10.3390/jcm12020610.
4
Otolaryngological manifestations of hospitalised patients with confirmed COVID-19 infection.确诊 COVID-19 感染住院患者的耳鼻喉科表现。
Eur Arch Otorhinolaryngol. 2021 May;278(5):1675-1685. doi: 10.1007/s00405-020-06396-8. Epub 2020 Oct 3.
5
Alteration of Smell and Taste in Asymptomatic and Symptomatic COVID-19 Patients in Sicily, Italy.意大利西西里岛无症状和有症状 COVID-19 患者的嗅觉和味觉改变。
Ear Nose Throat J. 2021 Apr;100(2_suppl):182S-185S. doi: 10.1177/0145561320981447. Epub 2020 Dec 22.
6
ENT manifestation in COVID-19 patients.COVID-19患者的耳鼻喉科表现。
Auris Nasus Larynx. 2020 Aug;47(4):559-564. doi: 10.1016/j.anl.2020.06.003. Epub 2020 Jun 15.
7
COVID-19 in otolaryngologist practice: a review of current knowledge.耳鼻喉科医生实践中的 COVID-19:当前知识综述。
Eur Arch Otorhinolaryngol. 2020 Jul;277(7):1885-1897. doi: 10.1007/s00405-020-05968-y. Epub 2020 Apr 18.
8
Prevalence of Loss of Smell and/or Taste and other Otorhinolaryngology Symptoms in COVID-19 Patients.新冠病毒感染者嗅觉和/或味觉丧失及其他耳鼻喉症状的流行情况。
Kathmandu Univ Med J (KUMJ). 2021 Apr-Jun;19(74):173-179.
9
Olfactory and Oral Manifestations of COVID-19: Sex-Related Symptoms-A Potential Pathway to Early Diagnosis.COVID-19 的嗅觉和口腔表现:与性别相关的症状——早期诊断的潜在途径。
Otolaryngol Head Neck Surg. 2020 Oct;163(4):722-728. doi: 10.1177/0194599820934380. Epub 2020 Jun 16.
10
Relationship between smoking and otorhinolaryngological symptoms.吸烟与耳鼻咽喉科症状之间的关系。
Kulak Burun Bogaz Ihtis Derg. 2016;26(1):28-33. doi: 10.5606/kbbihtisas.2016.87059.

引用本文的文献

1
Characteristics of Tinnitus in Patients Affected by COVID-19: A Systematic Review.新型冠状病毒肺炎患者耳鸣的特征:一项系统综述
Int Arch Otorhinolaryngol. 2025 Aug 20;29(3):1-20. doi: 10.1055/s-0045-1802968. eCollection 2025 Jul.
2
Post COVID-19 and Long COVID Symptoms in Otorhinolaryngology-A Narrative Review.新型冠状病毒肺炎康复后及长期新冠症状在耳鼻咽喉科的叙述性综述
J Clin Med. 2025 Jan 14;14(2):506. doi: 10.3390/jcm14020506.
3
Tinnitus and COVID-19: effect of infection, vaccination, and the pandemic.耳鸣与新冠病毒:感染、疫苗接种及疫情的影响

本文引用的文献

1
Otologic dysfunction in patients with COVID-19: A systematic review.新型冠状病毒肺炎患者的耳科功能障碍:一项系统综述。
Laryngoscope Investig Otolaryngol. 2020 Nov 17;5(6):1192-1196. doi: 10.1002/lio2.498. eCollection 2020 Dec.
2
Severity of Anosmia as an Early Symptom of COVID-19 Infection May Predict Lasting Loss of Smell.嗅觉减退作为新冠病毒感染的早期症状,其严重程度可能预示着嗅觉的永久性丧失。
Front Med (Lausanne). 2020 Nov 24;7:582802. doi: 10.3389/fmed.2020.582802. eCollection 2020.
3
COVID-19 and Tinnitus.COVID-19 与耳鸣。
Front Public Health. 2024 Nov 26;12:1508607. doi: 10.3389/fpubh.2024.1508607. eCollection 2024.
4
Clinical Profile and Outcome Analysis of Ear-Nose-Throat Symptoms in SARS-CoV-2 Omicron Subvariant Infections.奥密克戎变异株感染的耳鼻咽喉症状的临床特征和转归分析。
Int J Public Health. 2023 Oct 10;68:1606403. doi: 10.3389/ijph.2023.1606403. eCollection 2023.
5
Effect of any form of steroids in comparison with that of other medications on the duration of olfactory dysfunction in patients with COVID-19: A systematic review of randomized trials and quasi-experimental studies.比较任何形式的类固醇与其他药物对 COVID-19 患者嗅觉功能障碍持续时间的影响:随机试验和准实验研究的系统评价。
PLoS One. 2023 Aug 2;18(8):e0288285. doi: 10.1371/journal.pone.0288285. eCollection 2023.
6
An online survey on clinical characteristics of otologic symptoms linked to COVID-19 infection.一项关于与 COVID-19 感染相关的耳科症状临床特征的在线调查。
Front Public Health. 2023 May 26;11:1184262. doi: 10.3389/fpubh.2023.1184262. eCollection 2023.
7
Correlation of ENT Symptoms with Age, Sex, and Anti-SARS-CoV-2 Antibody Titer in Plasma.耳鼻喉症状与年龄、性别及血浆中抗SARS-CoV-2抗体滴度的相关性
J Clin Med. 2023 Jan 12;12(2):610. doi: 10.3390/jcm12020610.
Ear Nose Throat J. 2021 Apr;100(2_suppl):160S-162S. doi: 10.1177/0145561320974849. Epub 2020 Dec 4.
4
Objective evaluation of the nasal mucosal secretion in COVID-19 patients with anosmia.目的评估 COVID-19 患者伴嗅觉丧失的鼻黏膜分泌物。
Ir J Med Sci. 2021 Aug;190(3):889-891. doi: 10.1007/s11845-020-02405-1. Epub 2020 Oct 19.
5
Gustatory Dysfunction: A Highly Specific and Smell-Independent Symptom of COVID-19.味觉功能障碍:新冠病毒病的一种高度特异性且与嗅觉无关的症状
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):2755-2757. doi: 10.1007/s12070-020-02182-4. Epub 2020 Sep 30.
6
Otolaryngological manifestations of hospitalised patients with confirmed COVID-19 infection.确诊 COVID-19 感染住院患者的耳鼻喉科表现。
Eur Arch Otorhinolaryngol. 2021 May;278(5):1675-1685. doi: 10.1007/s00405-020-06396-8. Epub 2020 Oct 3.
7
Dizziness and COVID-19.头晕与新型冠状病毒肺炎
Ear Nose Throat J. 2021 Jan;100(1):29-30. doi: 10.1177/0145561320959573. Epub 2020 Sep 15.
8
Anosmia: an evolution of our understanding of its importance in COVID-19 and what questions remain to be answered.嗅觉丧失:对其在 COVID-19 中的重要性的认识的演变,以及仍有待回答的问题。
Eur Arch Otorhinolaryngol. 2021 Jul;278(7):2187-2191. doi: 10.1007/s00405-020-06285-0. Epub 2020 Sep 9.
9
Effect of Covid-19 in Otorhinolaryngology Practice: A Review.新型冠状病毒肺炎对耳鼻咽喉科临床实践的影响:综述
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):2699-2702. doi: 10.1007/s12070-020-02040-3. Epub 2020 Aug 18.
10
Criteria for establishing an association between Covid-19 and hearing loss.确定新冠病毒与听力损失之间关联的标准。
Am J Otolaryngol. 2020 Nov-Dec;41(6):102658. doi: 10.1016/j.amjoto.2020.102658. Epub 2020 Aug 9.