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新冠病毒感染者的耳鼻喉相关症状,重点是嗅觉和/或味觉丧失。

Ear nose throat-related symptoms with a focus on loss of smell and/or taste in COVID-19 patients.

机构信息

Istanbul Aydin University, Faculty of Medicine, Department of Otorhinolaryngology, Istanbul, Turkey.

Istanbul Aydin University, Faculty of Medicine, Department of Otorhinolaryngology, Istanbul, Turkey.

出版信息

Am J Otolaryngol. 2020 Nov-Dec;41(6):102622. doi: 10.1016/j.amjoto.2020.102622. Epub 2020 Jun 23.

Abstract

PURPOSE

To determine the frequency and severity of general and ear nose throat (ENT)- related symptoms, especially smell and/or loss of sense of taste (STL) in COVID-19 disease, as well as to investigate the recovery process of STL.

MATERIALS AND METHODS

Patients with a positive COVID-19 diagnosis were given a questionnaire consisting of general questions (age, sex, date of symptoms, smoking history, concomitant diseases), questions about the most obvious symptom at presentation (one option only), the severity and frequency of symptoms (general and ENT), and STL (recovery time and degree of recovery).

RESULTS

The study population consisted of 172 patients, 18-65 years old (mean age, 37.8 ± 12.5 years; 51.2% female; 76.2% nonsmokers). Cough (n = 30, 17.4%) and loss of sense of smell (n = 18, 10.4%) were the most obvious general and ENT symptoms, respectively. Eighty-eight patients (51.2%) reported loss of sense of smell, and 81 patients (47.1%) reported loss of sense of taste. The mean recovery times for loss of sense of smell and loss of sense of taste were 8.02 ± 6.41 and 8.20 ± 7.07 days, respectively. The loss of sense of smell and loss of sense of taste were the unique symptoms in four (4.54%) and one (1.23%) patients, respectively.

CONCLUSION

STL is a common symptom in COVID-19 and may be the first and/or only symptom of this disease. In patients presenting with STL complaints, surveillance for possible COVID-19 disease and screening tests will facilitate the struggle against the disease.

摘要

目的

确定 COVID-19 疾病中一般和耳鼻喉(ENT)相关症状的频率和严重程度,特别是嗅觉和/或味觉丧失(STL),并调查 STL 的恢复过程。

材料和方法

对 COVID-19 阳性诊断的患者进行问卷调查,问卷包括一般问题(年龄、性别、症状出现日期、吸烟史、合并症)、就诊时最明显症状(仅选一项)、症状严重程度和频率(一般和 ENT)以及 STL(恢复时间和恢复程度)。

结果

研究人群由 172 名 18-65 岁(平均年龄 37.8±12.5 岁;51.2%为女性;76.2%为不吸烟者)的患者组成。最明显的一般和 ENT 症状分别为咳嗽(n=30,17.4%)和嗅觉丧失(n=18,10.4%)。88 名患者(51.2%)报告嗅觉丧失,81 名患者(47.1%)报告味觉丧失。嗅觉丧失和味觉丧失的平均恢复时间分别为 8.02±6.41 和 8.20±7.07 天。嗅觉丧失和味觉丧失是 4 名(4.54%)和 1 名(1.23%)患者的独特症状。

结论

STL 是 COVID-19 的常见症状,可能是该疾病的首发和/或唯一症状。在出现 STL 症状的患者中,对可能的 COVID-19 疾病进行监测和筛查测试将有助于对抗该疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73c/7309902/ede5b5235d29/gr1_lrg.jpg

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