Leis H P
Surg Clin North Am. 1978 Aug;58(4):833-41. doi: 10.1016/s0039-6109(16)41595-1.
The true incidence of bilateral breast cancer, both simultaneous and subsequent, is higher than older statistics indicate, and the frequency can be expected to increase as more efficient methods of detection and treatment become commonplace. Furthermore, there is a subgroup of patients who have an especially high risk for having a second primary cancer in the other breast; if such a cancer develops it deleteriously influences the survival of the patient. A rational approach to the management of the other breast is presented using contralateral biopsy as an added modality for detection and reserving prophylatic matectomy of the other breast for those patients who ar at high risk for developing cancer in it.
双侧乳腺癌（同时性和异时性）的实际发病率高于以往统计数据所示，并且随着更有效的检测和治疗方法变得普遍，预计其发生率还会增加。此外，有一部分患者在另一侧乳房发生第二原发性癌症的风险特别高；如果发生这种癌症，会对患者的生存产生不利影响。本文提出了一种针对另一侧乳房的合理管理方法，即采用对侧活检作为额外的检测手段，并为那些另一侧乳房发生癌症风险高的患者保留预防性乳房切除术。
