RD3 Unit of Pharmacognosy, Bioanalysis and Drug Discovery, Faculty of Pharmacy, Campus Plaine, Université Libre de Bruxelles, 1050 Brussels, Belgium.
APFP, Faculty of Pharmacy, Campus Plaine, Université Libre de Bruxelles, 1050 Brussels, Belgium.
Molecules. 2022 May 14;27(10):3152. doi: 10.3390/molecules27103152.
While coffee beans have been studied for many years, researchers are showing a growing interest in coffee leaves and by-products, but little information is currently available on coffee species other than and . The aim of this work was to perform a targeted and untargeted metabolomics study on , and . The application of the recent high-resolution mass spectrometry-based metabolomics tools allowed us to gain a clear overview of the main differences among the coffee species. The results showed that the leaves and fruits of had a different metabolite profile when compared to the two other species. In , caffeine levels were found in lower concentrations while caffeoylquinic acid and mangiferin-related compounds were found in higher concentrations. A large number of specialized metabolites can be found in tissues, making this species a valid candidate for innovative healthcare products made with coffee extracts.
虽然咖啡豆已经研究了很多年，但研究人员对咖啡叶和副产品的兴趣日益浓厚，但目前关于除 和 以外的咖啡品种的信息很少。本工作的目的是对 、 和 进行靶向和非靶向代谢组学研究。最近基于高分辨率质谱的代谢组学工具的应用使我们能够清楚地了解咖啡品种之间的主要差异。结果表明，与其他两个品种相比， 和 的叶和果实具有不同的代谢物特征。在 中，咖啡因的浓度较低，而咖啡酰奎宁酸和芒果苷相关化合物的浓度较高。在 组织中可以发现大量的特殊代谢产物，这使该品种成为具有咖啡提取物的创新保健产品的候选者。
