Ferreira Tiago R, Sacks David L
Intracellular Parasite Biology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA.
Pathogens. 2022 May 14;11(5):580. doi: 10.3390/pathogens11050580.
Despite major advances over the last decade in our understanding of reproductive strategies, the sexual cycle in has defied direct observation and remains poorly investigated due to experimental constraints. Here, we summarize the findings and conclusions drawn from genetic analysis of experimental hybrids generated in sand flies and highlight the recent advances in generating hybrids in vitro. The ability to hybridize between culture forms of different species and strains of should invite more intensive investigation of the mechanisms underlying genetic exchange and provide a rich source of recombinant parasites for future genetic analyses.
尽管在过去十年里我们对生殖策略的理解取得了重大进展，但由于实验限制，[具体生物]的性周期仍无法直接观察，且研究较少。在此，我们总结了从白蛉实验杂交种的遗传分析中得出的发现和结论，并强调了体外产生杂交种的最新进展。不同物种和品系的[具体生物]培养形式之间进行杂交的能力，应该会引发对基因交换潜在机制的更深入研究，并为未来的遗传分析提供丰富的重组寄生虫来源。
