Arnold Elizabeth Mayfield, Bridges S Kate, Goldbeck Cameron, Norwood Peter, Swendeman Dallas, Rotheram-Borus Mary Jane
Department of Family and Community Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Center for HIV Identification, Prevention, and Treatment Services, University of California Los Angeles, Los Angeles, CA 90024, USA.
Vaccines (Basel). 2022 May 20;10(5):815. doi: 10.3390/vaccines10050815.
Human papillomavirus (HPV) is epidemic among young people, especially those at highest risk of acquiring HPV-related cancers.
Youth aged 14-24 years old ( = 1628) were recruited from 13 clinics, community agencies, and social media sites in Los Angeles, California, and New Orleans, Louisiana, that specialized in serving sexual and gender minority youths (SGMY), especially males at risk for HIV. A cross-sectional comparison of sociodemographic and risk histories of HPV vaccinated/unvaccinated youths was conducted using both univariate and multivariate regressions.
About half (51.9%) of youth were vaccinated, with similar percentages across states and across genders. Sexual and gender minority youths (SGMY, i.e., gay, bisexual, transgender, and non-heterosexual; 68.8%) and their heterosexual peers (15%) were equally likely to be vaccinated (54%), even though their risk for HPV-related cancers is very different. Vaccinations were higher among younger youth, those not using condoms, youth with greater education, that possessed a primary health care provider, and youth diagnosed with HIV. Vaccinations were lower among youth that were out-of-home due to mental health inpatient hospitalization, drug treatment, homelessness, or incarceration.
Special programs are required to target youth experiencing multiple life stressors, especially out-of-home experiences, those with less education, and without the safety net of health insurance or a provider.
人乳头瘤病毒（HPV）在年轻人中流行，尤其是那些感染HPV相关癌症风险最高的人群。
从加利福尼亚州洛杉矶市和路易斯安那州新奥尔良市的13家诊所、社区机构和社交媒体网站招募了14至24岁的年轻人（n = 1628），这些机构专门为性少数和性别少数青年（SGMY）提供服务，尤其是有感染艾滋病毒风险的男性。使用单变量和多变量回归对接种/未接种HPV疫苗的年轻人的社会人口统计学和风险史进行横断面比较。
约一半（51.9%）的年轻人接种了疫苗，各州和各性别之间的比例相似。性少数和性别少数青年（SGMY，即男同性恋、双性恋、跨性别者和非异性恋者；68.8%）及其异性恋同龄人（15%）接种疫苗的可能性相同（54%），尽管他们感染HPV相关癌症的风险差异很大。较年轻的年轻人、不使用避孕套的年轻人、受教育程度较高的年轻人、有初级医疗保健提供者的年轻人以及被诊断出感染艾滋病毒的年轻人的疫苗接种率较高。因心理健康住院、药物治疗、无家可归或监禁而离家的年轻人的疫苗接种率较低。
需要制定特别计划，以针对经历多种生活压力因素的年轻人，尤其是离家经历、教育程度较低且没有医疗保险或医疗服务提供者安全保障的年轻人。
