比较流感病毒生物学以了解 D 型流感病毒。
Comparing Influenza Virus Biology for Understanding Influenza D Virus.
机构信息
Division of Basic Biomedical Sciences, University of South Dakota, Vermillion, SD 57069, USA.
出版信息
Viruses. 2022 May 13;14(5):1036. doi: 10.3390/v14051036.
The newest type of influenza virus, influenza D virus (IDV), was isolated in 2011. IDV circulates in several animal species worldwide, causing mild respiratory illness in its natural hosts. Importantly, IDV does not cause clinical disease in humans and does not spread easily from person to person. Here, we review what is known about the host-pathogen interactions that may limit IDV illness. We focus on early immune interactions between the virus and infected host cells in our summary of what is known about IDV pathogenesis. This work establishes a foundation for future research into IDV infection and immunity in mammalian hosts.
新型流感病毒，即 D 型流感病毒（IDV）于 2011 年被分离出来。IDV 在世界范围内的多种动物物种中传播，导致其自然宿主出现轻微的呼吸道疾病。重要的是，IDV 不会在人类中引起临床疾病，也不容易在人与人之间传播。在这里，我们回顾了宿主-病原体相互作用的已知情况，这些相互作用可能限制了 IDV 疾病的发生。我们专注于病毒与受感染宿主细胞之间的早期免疫相互作用，概述了 IDV 发病机制的已知情况。这项工作为未来在哺乳动物宿主中研究 IDV 感染和免疫奠定了基础。
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