糖尿病患者在三级医院的糖尿病视网膜病变：描述性横断面研究。

Diabetic Retinopathy among Diabetic Patients at a Tertiary Care Hospital: A Descriptive Cross-sectional Study.

机构信息

Department of Ophthalmology, Chitwan Medical College, Bharatpur-10, Chitwan, Nepal.

Department of Endocrinology, Chitwan Medical College, Bharatpur-10, Chitwan, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2022 Mar 11;60(247):234-240. doi: 10.31729/jnma.7243.

DOI:10.31729/jnma.7243

PMID:35633262

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9226743/

Abstract

INTRODUCTION

The alarming rise in the prevalence of diabetes mellitus is a global public health and economic problem. Diabetic retinopathy is the most common ocular morbidity in the diabetic population and is the leading cause of blindness among the working-age group. This study was aimed to find out the prevalence of diabetic retinopathy in diabetic patients attending to the department of ophthalmology of a tertiary care hospital.

METHODS

A descriptive cross-sectional study was conducted in the Department of Ophthalmology of a tertiary care hospital from 15th August to 30th November 2021. Ethical clearance was taken from the Institutional Review Committee (Reference number: CMC-IRC/078/079-021). Convenience sampling was done. Basic demographic data, risk factors, clinical characteristics, and prevalence of diabetic retinopathy were noted. Data entry was done using Statistical Package for the Social Sciences version 26.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data.

RESULTS

Among 540 participants, 146 (27.04%) (23.29-30.79 at 95% Confidence Interval) study subjects had diabetic retinopathy changes in at least one eye. Smoking in 88 (60.27%), type 2 diabetes mellitus in 139 (95.21%), hypertension in 85 (58.22%), raised glycated hemoglobin levels in 120 (82.19%) were the major factors observed in the study subjects.

CONCLUSIONS

The prevalence of diabetic retinopathy was higher in our study when compared to national studies.

KEYWORDS

biomarkers; body mass index; diabetes mellitus; diabetic retinopathy; visual acuity.

摘要

简介

糖尿病患病率的惊人上升是一个全球性的公共卫生和经济问题。糖尿病视网膜病变是糖尿病患者中最常见的眼部疾病，也是导致工作年龄段人群失明的主要原因。本研究旨在调查在一家三级保健医院眼科就诊的糖尿病患者中糖尿病视网膜病变的患病率。

方法

2021 年 8 月 15 日至 11 月 30 日，在一家三级保健医院的眼科进行了一项描述性横断面研究。本研究已获得机构审查委员会的伦理批准（参考编号：CMC-IRC/078/079-021）。采用便利抽样法。记录基本人口统计学数据、危险因素、临床特征以及糖尿病视网膜病变的患病率。使用社会科学统计软件包 26.0 进行数据录入。计算了 95%置信区间的点估计值，以及二进制数据的频率和百分比。

结果

在 540 名参与者中，146 名（27.04%）（95%置信区间为 23.29-30.79）至少一只眼有糖尿病视网膜病变改变。研究对象中观察到的主要因素包括吸烟 88 例（60.27%）、2 型糖尿病 139 例（95.21%）、高血压 85 例（58.22%）、糖化血红蛋白升高 120 例（82.19%）。