Veterinary Medical Research Institute, Hungária krt 21, 1143, Budapest, Hungary.
Conservation and Veterinary Services, Budapest Zoo and Botanical Garden, Állatkerti krt. 6-12, 1164, Budapest, Hungary.
Arch Virol. 2022 Aug;167(8):1721-1724. doi: 10.1007/s00705-022-05478-8. Epub 2022 May 28.
In this study, the complete genome of a novel polyomavirus detected in a great cormorant (Phalacrocorax carbo) was characterized. The 5133-bp-long genome of the cormorant polyomavirus has a genomic structure typical of members of the genus Gammapolyomavirus, family Polyomaviridae, containing open reading frames encoding the large and small tumor antigens, viral proteins 1, 2, and 3, and the X protein. The large tumor antigen of the cormorant polyomavirus shares 45.6-50.4% amino acid sequence identity with the homologous sequences of other gammapolyomaviruses. These data, together with results of phylogenetic analysis, suggest that this cormorant polyomavirus should be considered the first member of a new species within the genus Gammapolyomavirus, for which we propose the name "Phalacrocorax carbo polyomavirus 1".
在这项研究中，我们对一种新型多瘤病毒进行了研究，该病毒是从一只大鸬鹚（Phalacrocorax carbo）中检测到的。这种鸬鹚多瘤病毒的基因组全长 5133 个碱基对，具有典型的γ多瘤病毒属成员的基因组结构，包含编码大、小肿瘤抗原、病毒蛋白 1、2 和 3 以及 X 蛋白的开放阅读框。鸬鹚多瘤病毒的大肿瘤抗原与其他γ多瘤病毒的同源序列具有 45.6-50.4%的氨基酸序列同一性。这些数据，加上系统发育分析的结果，表明这种鸬鹚多瘤病毒应该被认为是γ多瘤病毒属中的一个新种的第一个成员，我们建议将其命名为“Phalacrocorax carbo polyomavirus 1”。
