从实验室结果预测 COVID-19 患者入住重症监护病房。
Predicting Intensive Care Unit Admission for COVID-19 Patients from Laboratory Results.
机构信息
Medical Department, Althagar General Hospital, Jeddah, Saudi Arabia.
Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
出版信息
Dis Markers. 2022 May 26;2022:4623901. doi: 10.1155/2022/4623901. eCollection 2022.
Trends in routine laboratory tests, such as high white blood cell and low platelet counts, correlate with COVID-19-related intensive care unit (ICU) admissions. Other related biomarkers include elevated troponin, alanine aminotransferase, and aspartate transaminase levels (liver function tests). To this end, the aim of this study was to investigate the effect of changes in laboratory test parameters on ward-based and ICU COVID-19 patients. A total of 280 COVID-19 patients were included in the study and were divided based on admission status into ICU (37) or ward (243) patients. ICU admission correlated significantly with higher levels of several tested parameters, including lactate dehydrogenase, creatinine, D-dimer, creatine kinase, white blood cell count, and neutrophil count. In conclusion, routine laboratory tests offer an indication of which COVID-19 patients are most likely to be admitted to the ICU. These associations can assist healthcare providers in addressing the needs of patients who are at risk of COVID-19 complications.
常规实验室检查指标的变化趋势，如白细胞计数升高和血小板计数降低，与 COVID-19 相关的重症监护病房（ICU）入院相关。其他相关生物标志物包括肌钙蛋白、丙氨酸氨基转移酶和天冬氨酸氨基转移酶水平（肝功能检查）升高。为此，本研究旨在探讨实验室检查参数变化对住院和 ICU COVID-19 患者的影响。共纳入 280 例 COVID-19 患者，并根据入院情况分为 ICU（37 例）或病房（243 例）患者。ICU 入院与多项检测参数水平升高显著相关，包括乳酸脱氢酶、肌酐、D-二聚体、肌酸激酶、白细胞计数和中性粒细胞计数。总之，常规实验室检查可提示哪些 COVID-19 患者最有可能入住 ICU。这些关联可以帮助医疗保健提供者满足有 COVID-19 并发症风险的患者的需求。
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