手术根覆盖治疗牙本质过敏症的疗效：系统评价和荟萃分析。

Effectiveness of surgical root coverage on dentin hypersensitivity: A systematic review and meta-analysis.

机构信息

Faculté des Sciences Médicales et Paramédicales, Ecole de Médecine Dentaire, Aix-Marseille Université, Provence-Alpes-Côte D'azur, Marseille, France.

Assistance Publique-Hopitaux de Marseille (AP-HM), Hopital Timone, Provence-Alpes-Côte D'azur, Marseille, France.

出版信息

J Clin Periodontol. 2022 Aug;49(8):840-851. doi: 10.1111/jcpe.13664. Epub 2022 Jun 5.

DOI:10.1111/jcpe.13664

PMID:35634650

Abstract

AIM

To assess the effect of surgical root coverage (RC) on dentin hypersensitivity (DH) associated with gingival recession.

MATERIALS AND METHODS

Two independent reviewers conducted electronic literature searches in MEDLINE (PubMed), EMBASE, Cochrane Library, Web Of Science, Dentistry & Oral Sciences Source, ScienceDirect, and ClinicalTrials.gov databases as well as a manual search to identify eligible clinical studies from January 2000 to March 2022. Randomized controlled trials (RCTs) comparing two surgical RC techniques or a surgical RC technique with or without adjuvant were included. Meta-analyses were performed on data provided by RCTs.

RESULTS

Thirteen RCTs with a total of 701 patients (1086 recessions) were included. The percentage of DH suppression was 70.8% (95% confidence interval [CI] [64.4-76.6]; I = 39.2% [3.5-61.8], Q-test = 0.02) after surgical RC. Recession reduction and percentage of RC were both statistically significantly associated with DH suppression (estimate = 0.66 [0.10-1.23], p = .022, R = 14.45% and estimate = 0.04 [0.01-0.08], p = .012, R = 29.54%, respectively). Coronally advanced flap (CAF) + connective tissue graft showed results statistically more effective than CAF + xenogeneic collagen matrix in DH suppression (73.3% [65.6-79.8] and 61.4% [51.7-70.3], respectively; p = .048).

CONCLUSIONS

Success of surgical RC is associated with DH suppression.

摘要

目的

评估手术根覆盖（RC）对与牙龈退缩相关的牙本质敏感（DH）的影响。

材料和方法

两位独立的审查员在 MEDLINE（PubMed）、EMBASE、Cochrane 图书馆、Web Of Science、Dentistry & Oral Sciences Source、ScienceDirect 和 ClinicalTrials.gov 数据库中进行了电子文献检索，并进行了手动搜索，以确定 2000 年 1 月至 2022 年 3 月期间符合条件的临床研究。纳入比较两种手术 RC 技术或一种手术 RC 技术联合或不联合辅助治疗的随机对照试验（RCT）。对 RCT 提供的数据进行了荟萃分析。

结果

纳入了 13 项 RCT，共 701 名患者（1086 个退缩）。手术 RC 后 DH 抑制率为 70.8%（95%置信区间 [64.4-76.6]；I 为 39.2% [3.5-61.8]，Q 检验 = 0.02）。退缩减少和 RC 百分比均与 DH 抑制显著相关（估计值=0.66 [0.10-1.23]，p=0.022，R²=14.45%和估计值=0.04 [0.01-0.08]，p=0.012，R²=29.54%）。冠向推进瓣（CAF）+组织工程胶原基质在 DH 抑制方面的效果明显优于 CAF+异种胶原基质（分别为 73.3%[65.6-79.8]和 61.4%[51.7-70.3]；p=0.048）。