Department of Otorhinolaryngology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Clin Otolaryngol. 2022 Sep;47(5):577-582. doi: 10.1111/coa.13950. Epub 2022 Jun 10.
The study aimed to analyse the hearing levels of patients with gout using extended high frequencies (EHFs) audiometry. Thus, we aimed to reveal the early detectability of potential hearing losses.
Comparative cross-sectional study.
A single centre patient was diagnosed with gout disease.
Two groups consisted of 32 patients with gout and 32 healthy volunteers.
The primary outcome was hearing thresholds in pure tone (PT) audiometry and EHFs audiometry. Also, the association between audiometric results and haematological and biochemical parameters were evaluated.
There was no significant difference between groups in terms of mean hearing thresholds in PT audiometry. But, at all frequencies above 4000 Hz (4000-18 000 Hz), the hearing thresholds were significantly higher in patients with gout. Also, the hearing thresholds above 8000 Hz were positively correlated with serum uric acid levels. Hearing thresholds at higher frequencies were positively correlated with haemoglobin levels and negatively correlated with high-density lipoprotein levels.
To our knowledge, this is the first study in the literature demonstrating the high frequency of hearing loss in patients with gout using EHFs audiometry. We consider that using EHFs audiometry should have an important place in the early detection of potential hearing losses in gout patients.
本研究旨在通过扩展高频（EHF）听力测试分析痛风患者的听力水平，从而揭示潜在听力损失的早期可检测性。
比较性横断面研究。
在单一中心，患者被诊断患有痛风疾病。
两组各有 32 名痛风患者和 32 名健康志愿者。
主要观察指标为纯音（PT）听力测试和 EHF 听力测试的听力阈值。同时，评估听力测试结果与血液学和生化参数之间的关系。
PT 听力测试中两组的平均听力阈值无显著差异。但是，在所有高于 4000 Hz（4000-18000 Hz）的频率下，痛风患者的听力阈值显著更高。此外，8000 Hz 以上的听力阈值与血清尿酸水平呈正相关。较高频率的听力阈值与血红蛋白水平呈正相关，与高密度脂蛋白水平呈负相关。
据我们所知，这是文献中首次使用 EHF 听力测试证明痛风患者听力损失高发的研究。我们认为，在痛风患者潜在听力损失的早期检测中，EHF 听力测试应该占有重要地位。
