营养摄入对伴有偏头痛和肠易激综合征的患者症状严重程度的潜在影响。
The potential impact of nutritional intake on symptoms severity in patients with comorbid migraine and irritable bowel syndrome.
机构信息
Department of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Department of Tropical medicine (Department of Gastroenterology, Hepatology and Endemic Medicine), Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
出版信息
BMC Neurol. 2022 May 30;22(1):199. doi: 10.1186/s12883-022-02723-0.
BACKGROUND
Specific dietary recommendations for migraine patients with comorbid irritable bowel syndrome (IBS) are lacking. This work aimed to study the severity scores of such two common pain-related disorders in relation to various macronutrients and micronutrients intake.
METHODS
A cross-sectional study was conducted on patients with concomitant migraine and IBS. The frequency and intensity of migraine attacks and the severity of IBS were evaluated. Data on dietary intake were collected using food frequency questionnaires and 24-hour dietary recall.
RESULTS
One-hundred patients with a median age of 36 years participated. The severity scores for migraine and IBS were positively correlated with fat and copper and negatively correlated with fiber and zinc intake. Copper intake was an independent predictor of the severity of both migraine and IBS (P 0.033, < 0.001). Patients with episodic migraine (n = 69) had a significantly higher frequency of cooked, fresh vegetables, and wheat bran bread intake (P 0.009, 0.004, 0.021) and lower frequency of hydrogenated oils intake (P 0.046), in comparison to patients with chronic migraine (n = 31). Patients with moderate intensity of migraine (n = 37) had a significantly higher frequency of herbal drinks intake (P 0.014) than patients with a severe intensity of migraine (n = 63). Patients with mild (n = 13) and moderate IBS (n = 41) had a significantly higher frequency of wheat bran bread and sen bread intake (P 0.003, 0.022) than patients with severe IBS (n = 46).
CONCLUSION
Patients with comorbid migraine and IBS are advised to adhere to a diet low in fat and copper and rich in fiber and zinc.
背景
目前缺乏针对同时患有偏头痛和肠易激综合征（IBS）的患者的具体饮食建议。本研究旨在研究这两种常见的与疼痛相关的疾病的严重程度与各种宏量营养素和微量营养素摄入之间的关系。
方法
对同时患有偏头痛和 IBS 的患者进行横断面研究。评估偏头痛发作的频率和强度以及 IBS 的严重程度。使用食物频率问卷和 24 小时膳食回顾收集饮食摄入数据。
结果
100 名中位年龄为 36 岁的患者参与了研究。偏头痛和 IBS 的严重程度评分与脂肪和铜呈正相关，与纤维和锌呈负相关。铜的摄入量是偏头痛和 IBS 严重程度的独立预测因素（P 0.033，<0.001）。与慢性偏头痛患者（n=31）相比，发作性偏头痛患者（n=69）摄入熟蔬菜、新鲜蔬菜和全麦面包的频率显著更高（P 0.009、0.004、0.021），而摄入氢化油的频率显著更低（P 0.046）。偏头痛严重程度为中度的患者（n=37）摄入草药饮料的频率显著高于偏头痛严重程度为重度的患者（n=63）（P 0.014）。偏头痛程度为轻度（n=13）和中度（n=41）的患者摄入全麦面包和酸面团面包的频率显著高于偏头痛程度为重度的患者（n=46）（P 0.003、0.022）。
结论
建议同时患有偏头痛和 IBS 的患者遵循低脂肪、低铜和高纤维、高锌的饮食。
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