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皮肤填充剂与新型冠状病毒肺炎：1例新型冠状病毒肺炎感染后出现血管性水肿伴荨麻疹的患者

Dermal Fillers and COVID-19: Angioedema With Urticaria in a Patient Post COVID-19 Infection.

作者信息

Virdi Gurnam

机构信息

Dermatology, Academy of Aesthetic Medicine, Sheffield, GBR.

出版信息

Cureus. 2022 Apr 25;14(4):e24461. doi: 10.7759/cureus.24461. eCollection 2022 Apr.

DOI:10.7759/cureus.24461
PMID:35637833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9131708/
Abstract

Hyaluronic acid dermal fillers are a very popular choice for patients wanting to undergo non-invasive facial rejuvenation. Its prevalence is predicted to continue to rise. We report a case of delayed angioedema and associated urticaria to hyaluronic acid dermal fillers post COVID-19 infection. To our knowledge, this is an unusual case of hypersensitivity reaction of eight-month latency. Although the aetiology warrants further research, the author suggests utilisation of a four-week time window between dermal filler injections and COVID-19 vaccination.

摘要

透明质酸真皮填充剂是希望接受非侵入性面部年轻化治疗的患者非常受欢迎的选择。预计其使用率将继续上升。我们报告了1例新型冠状病毒肺炎感染后透明质酸真皮填充剂引发迟发性血管性水肿及相关荨麻疹的病例。据我们所知，这是1例潜伏期长达8个月的罕见超敏反应病例。尽管病因有待进一步研究，但作者建议在真皮填充剂注射和新型冠状病毒肺炎疫苗接种之间留出4周的时间间隔。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfa1/9131708/d47fbd5f43b1/cureus-0014-00000024461-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfa1/9131708/d47fbd5f43b1/cureus-0014-00000024461-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfa1/9131708/d47fbd5f43b1/cureus-0014-00000024461-i01.jpg

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J Am Acad Dermatol. 2021 Jul;85(1):46-55. doi: 10.1016/j.jaad.2021.03.092. Epub 2021 Apr 7.
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Autoimmune/inflammatory syndrome induced by adjuvants-ASIA-related to biomaterials: analysis of 45 cases and comprehensive review of the literature.佐剂相关性免疫/炎症综合征（ASIA）相关生物材料：45 例分析及文献综述
Immunol Res. 2018 Feb;66(1):120-140. doi: 10.1007/s12026-017-8980-5.
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