Ashraf Muhammed Paxshan, Karim Hawnaz Atta, Majeed Nasrin Ghafar, Tahir Kosar Shirwan, Abdullah Shnow Hussain, Abdul Aziz Jeza M, Makram Abdelrahman M, Huy Nguyen Tien
Baxshin Research Center, Baxshin Hospital, Sulaimani, Kurdistan Region, Iraq.
Medical Laboratory Science, College of Health Sciences, University of Human Development, Sulaimani, Kurdistan Region, Iraq.
Ann Med Surg (Lond). 2022 May 4;77:103720. doi: 10.1016/j.amsu.2022.103720. eCollection 2022 May.
Smooth muscle tumors of the vulva are more difficult to diagnose and are frequently mistaken as Bartholin cysts prior to surgery.
A 41-year-old female presented with a left vulvar mass that increased in size compared to the previous year. The patient had normal urination and a regular menstrual cycle. The presentation was not associated with dyspareunia, abnormal bleeding, and signs of infection (e.g., fever, vaginal discharge). The history of any sexually transmitted disease was inconclusive. There was also no family history of malignancy. Physical examination showed a solitary swelling mass, measuring 5 × 2 cm in the left labia majora at the site of the Bartholin gland. The mass was firm in consistency, partially movable, and non-tender with no inguinal lymphadenopathy. Histopathology after surgical removal revealed a benign vulvar leiomyoma.
Labia majora leiomyoma at the site of the Bartholin gland is rather uncommon. Some cases can develop into atypical leiomyoma or even leiomyosarcoma with local tissue infiltration.
If the clinical picture is unusual, it is better to send the patient for ultrasound and MRI to exclude other causes followed by performing wide local surgical excision of the mass to allow proper histopathological and/or immunohistochemistry examination to differentiate between benign and malignant tumors.
外阴平滑肌瘤更难诊断,在手术前常被误诊为巴氏腺囊肿。
一名41岁女性,左侧外阴肿物较前一年增大。患者排尿正常,月经周期规律。此次表现与性交困难、异常出血及感染迹象(如发热、阴道分泌物)无关。任何性传播疾病史均不明确。也无恶性肿瘤家族史。体格检查发现左侧大阴唇巴氏腺部位有一孤立性肿胀肿物,大小为5×2厘米。肿物质地硬,部分可活动,无压痛,腹股沟无淋巴结肿大。手术切除后的组织病理学检查显示为良性外阴平滑肌瘤。
巴氏腺部位的大阴唇平滑肌瘤相当少见。一些病例可发展为非典型平滑肌瘤甚至平滑肌肉瘤,并伴有局部组织浸润。
如果临床表现不寻常,最好先让患者进行超声和磁共振成像检查以排除其他病因,然后对肿物进行广泛局部手术切除,以便进行适当的组织病理学和/或免疫组化检查,以区分良性和恶性肿瘤。