一名47岁蛋白S缺乏男性的肠系膜上静脉血栓形成：病例报告。
Superior mesenteric venous thrombosis in a 47 years old male with protein S deficiency: A case report.
作者信息
Bhattarai Ayush Mohan, Bhattarai Ashish Mohan, Karki Abinash, Baral Smarika, Poudel Sabin, Adhikari Samikshya
机构信息
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Department of Radiology, Nobel Medical College, Biratnagar, Nepal.
出版信息
Ann Med Surg (Lond). 2022 May 3;77:103719. doi: 10.1016/j.amsu.2022.103719. eCollection 2022 May.
INTRODUCTION
Mesenteric venous thrombosis is due to blood clot in veins that drain blood from the intestine. It may lead to mesenteric ischemia. Protein S deficiency is one of the causes of superior mesenteric vein thrombosis.
CASE PRESENTATION
A 47 years old male patient presented with pain in the abdomen. Contrast CECT shows filling defect in the superior mesenteric venous thrombosis. Coagulometer showed lower protein S activity than that of normal.
CLINICAL DISCUSSION
Proper diagnosis is needed for early detection so that proper intervention can be made on time. Anticoagulation and vitamin K antagonists are given.
CONCLUSIONS
Though rare, protein S deficiency should be considered a possible cause of mesenteric venous thrombosis.
引言
肠系膜静脉血栓形成是由于从肠道引流血液的静脉中出现血凝块。它可能导致肠系膜缺血。蛋白S缺乏是肠系膜上静脉血栓形成的原因之一。
病例介绍
一名47岁男性患者出现腹部疼痛。增强CT血管造影显示肠系膜上静脉血栓形成有充盈缺损。凝血仪显示蛋白S活性低于正常水平。
临床讨论
需要进行正确诊断以便早期发现，从而能够及时进行适当干预。给予抗凝治疗和维生素K拮抗剂。
结论
尽管罕见，但蛋白S缺乏应被视为肠系膜静脉血栓形成的可能原因。
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