Sherman K J, Daling J R, Weiss N S
Sex Transm Dis. 1987 Jan-Mar;14(1):12-6. doi: 10.1097/00007435-198701000-00003.
To evaluate the association of genital herpes, genital warts, gonorrhea, and trichomoniasis with the occurrence of subsequent tubal infertility, 321 women who had tubal infertility were interviewed concerning their history of these sexually transmitted diseases (STD). The responses were compared to those of women who conceived children during the period the infertile women began trying to become pregnant. By a multivariate analysis, the comparisons were controlled for several confounding variables (e.g., use of an intrauterine device, cigarette smoking, number of prior pregnancies, number of sexual partners, and a history of the other STD). The risk of tubal infertility in women who reported at least one episode of gonorrhea after their last pregnancy, relative to that among other women, was 2.8 (95% confidence interval = 1.3-5.7). The relative risk of tubal infertility was also higher among women who reported a history of trichomoniasis (relative risk = 1.4; 95% confidence interval = 1.0-2.5) or genital warts (relative risk = 1.9; 95% confidence interval = 1.0-3.6).
为评估生殖器疱疹、尖锐湿疣、淋病和滴虫病与随后发生输卵管性不孕之间的关联，对321名患有输卵管性不孕的女性就这些性传播疾病（STD）病史进行了访谈。将这些女性的回答与在不孕女性开始尝试怀孕期间成功受孕的女性的回答进行了比较。通过多变量分析，对几种混杂变量（例如，宫内节育器的使用、吸烟、既往怀孕次数、性伴侣数量以及其他性传播疾病病史）进行了对照比较。相对于其他女性，在最后一次怀孕后报告至少有一次淋病发作的女性发生输卵管性不孕的风险为2.8（95%置信区间=1.3 - 5.7）。报告有滴虫病病史（相对风险=1.4；95%置信区间=1.0 - 2.5）或尖锐湿疣病史（相对风险=1.9；95%置信区间=1.0 - 3.6）的女性发生输卵管性不孕的相对风险也较高。
