Daling J R, Weiss N S, Voigt L, Spadoni L R, Soderstrom R, Moore D E, Stadel B V
Fertil Steril. 1985 Mar;43(3):389-94. doi: 10.1016/s0015-0282(16)48437-2.
One hundred twenty-seven women who had been given diagnoses of tubal infertility between 1979 and 1981 in King County, Washington, yet previously had been pregnant, were interviewed to determine their prior history of legally induced abortion. Their responses were compared with those of 395 women who conceived a child at the same time the infertile women began their unsuccessful attempt to become pregnant. In making the comparison, we adjusted for the effects of variables that in this population were related both to having an induced abortion and to the occurrence of infertility, i.e., age, number of prior pregnancies, number of sexual partners, cigarette smoking habits, Dalkon Shield (A. H. Robins Company, Richmond, VA) use, and whether the woman worked outside the home. The risk of tubal infertility in women who had had an induced abortion was not increased above that of other women (relative risk, 1.15; 95% confidence interval, 0.70 to 1.89). For women with two or more abortions, the relative risk was 1.29 (95% confidence interval, 0.39 to 4.20). When only the most recent pregnancy was considered, the relative risk was 1.19 (95% confidence interval, 0.72 to 1.97). Our results suggest that legal abortion, as performed during the past decade in the United States, does not carry an excess risk for future tubal infertility.
1979年至1981年间，在华盛顿州金县被诊断为输卵管性不孕但此前曾怀孕的127名女性接受了访谈，以确定她们既往合法人工流产史。将她们的回答与395名女性的回答进行比较，这395名女性在这些不孕女性开始尝试怀孕但未成功的同时怀孕。在进行比较时，我们对该人群中与人工流产和不孕发生均相关的变量的影响进行了调整，即年龄、既往怀孕次数、性伴侣数量、吸烟习惯、使用Dalkon Shield（弗吉尼亚州里士满的A.H.罗宾斯公司生产）以及女性是否外出工作。有过人工流产史的女性发生输卵管性不孕的风险并未高于其他女性（相对风险为1.15；95%置信区间为0.70至1.89）。对于有两次或更多次流产的女性，相对风险为1.29（95%置信区间为0.39至4.20）。仅考虑最近一次怀孕时，相对风险为1.19（95%置信区间为0.72至1.97）。我们的结果表明，过去十年在美国进行的合法人工流产不会增加未来发生输卵管性不孕的额外风险。
