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在出现值得关注的新型严重急性呼吸综合征冠状病毒2（SARS-CoV-2）变体的时代，安大略省各地污水处理设施进水的宏基因组学研究

Metagenomics of Wastewater Influent from Wastewater Treatment Facilities across Ontario in the Era of Emerging SARS-CoV-2 Variants of Concern.

作者信息

Lawal Opeyemi U, Zhang Linkang, Parreira Valeria R, Brown R Stephen, Chettleburgh Charles, Dannah Nora, Delatolla Robert, Gilbride Kimberly A, Graber Tyson E, Islam Golam, Knockleby James, Ma Sean, McDougall Hanlan, McKay R Michael, Mloszewska Aleksandra, Oswald Claire, Servos Mark, Swinwood-Sky Megan, Ybazeta Gustavo, Habash Marc, Goodridge Lawrence

机构信息

Canadian Research Institute for Food Safety, Department of Food Science, University of Guelph, Guelph, Ontario, Canada.

Department of Chemistry, Queen's University, Kingston, Ontario, Canada.

出版信息

Microbiol Resour Announc. 2022 Jul 21;11(7):e0036222. doi: 10.1128/mra.00362-22. Epub 2022 May 31.

DOI:10.1128/mra.00362-22
PMID:35638829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9302097/
Abstract

We report metagenomic sequencing analyses of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in composite wastewater influent from 10 regions in Ontario, Canada, during the transition between Delta and Omicron variants of concern. The Delta and Omicron BA.1/BA.1.1 and BA.2-defining mutations occurring in various frequencies were reported in the consensus and subconsensus sequences of the composite samples.

摘要

我们报告了在加拿大安大略省10个地区的复合废水进水样本中，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）RNA的宏基因组测序分析结果，该分析处于值得关注的德尔塔变异株和奥密克戎变异株过渡期间。在复合样本的共识序列和亚共识序列中，报告了以不同频率出现的德尔塔、奥密克戎BA.1/BA.1.1和BA.2特征性突变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5392/9302097/a80b7c737ea9/mra.00362-22-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5392/9302097/a80b7c737ea9/mra.00362-22-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5392/9302097/a80b7c737ea9/mra.00362-22-f001.jpg

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