在庭园葱蜗牛和红蛞蝓中磺胺异恶唑的乙酰化和羟基化作用
Acetylation and hydroxylation of sulphatroxazole in the snail Cepaea hortensis and the slug Arion rufus.
作者信息
Vree T B, Vree M L, Nouws J F
出版信息
Vet Q. 1987 Jan;9(1):88-90. doi: 10.1080/01652176.1987.9694082.
PMID:3564322
Abstract
The snail Cepaea hortensis can acetylate and hydroxylate sulphatroxazole via a pathway similar to that in man. The principal metabolic pathways, in order of decreasing rate, are hydroxylation, glucuronidation and acetylation. The slug Arion rufus also can acetylate and hydroxylate sulphatroxazole, although, in contrast to the snail, is rate of acetylation is higher than that of hydroxylation.
摘要
蜗牛园螺可以通过与人类相似的途径对磺胺异恶唑进行乙酰化和羟基化。主要代谢途径按速率递减顺序依次为羟基化、葡萄糖醛酸化和乙酰化。鼻涕虫红蛞蝓也能对磺胺异恶唑进行乙酰化和羟基化，不过，与蜗牛不同的是，它的乙酰化速率高于羟基化速率。
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